Evidence map›Paper›PMID 26919828›Full record

ArticleMalaria journal2016

Anopheles subpictus carry human malaria parasites in an urban area of Western India and may facilitate perennial malaria transmission.

Ashwani Kumar, Rajeshwari Hosmani, Shivaji Jadhav, Trelita de Sousa, Ajeet Mohanty, Milind Naik, Adarsh Shettigar, Satyajit Kale, Neena Valecha, Laura Chery and 1 more

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  7. Anopheles jamesii Supports Plasmodium vivax Sporogony under Laboratory Conditions.The American journal of tropical medicine and hygiene · 2024
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  14. Seasonal dynamics ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Ashwani KumarNational Institute of Malaria Research, Field Unit, Campal, Goa, India. ashwani07@gmail.com.
Rajeshwari HosmaniNational Institute of Malaria Research, Field Unit, Campal, Goa, India. rajeshwari.hraj@gmail.com.
Shivaji JadhavNational Institute of Malaria Research, Field Unit, Campal, Goa, India. scientistshivaji@gmail.com.
Trelita de SousaNational Institute of Malaria Research, Field Unit, Campal, Goa, India. trelita@gmail.com.
Ajeet MohantyNational Institute of Malaria Research, Field Unit, Campal, Goa, India. ajitbiotech1@gmail.com.
Milind NaikNational Institute of Malaria Research, Field Unit, Campal, Goa, India. milindnaik4@gmail.com.
Adarsh ShettigarNational Institute of Malaria Research, Field Unit, Campal, Goa, India. shettigaradu@gmail.com.
Satyajit KaleNational Institute of Malaria Research, Field Unit, Campal, Goa, India. kalesatyajit@yahoo.com.
Neena ValechaNational Institute of Malaria Research (ICMR), Sector 8, Dwarka, New Delhi, India. neenavalecha@gmail.com.
Laura CheryDepartment of Chemistry, University of Washington, Seattle, WA, USA. chery@chem.washington.edu.
Pradipsinh K RathodDepartment of Chemistry, University of Washington, Seattle, WA, USA. rathod@chem.washington.edu.
National Institute of Malaria Research · INUniversity of Washington · US

Funding

Shared TechnologyU19AI089688 · NIAID · UNIVERSITY OF WASHINGTON · PI RATHOD, PRADIPSINH K. · 2010 to 2023
$22.4M
IDENTIFICATION OF THE LIGAND FOR CD6F32AI008688 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SINGER, NORA · 1992 to 1994
–
NIAID NIH HHS U19AI08688NIAID NIH HHS U19 AI089688
6 · The paper itself

Abstract

backgroundIndia contributes 1.5-2 million annual confirmed cases of malaria. Since both parasites and vectors are evolving rapidly, updated information on parasite prevalence in mosquitoes is important for vector management and disease control. Possible new vector-parasite interactions in Goa, India were tested.

methodsA total of 1036 CDC traps were placed at four malaria endemic foci in Goa, India from May 2013 to April 2015. These captured 23,782 mosquitoes, of which there were 1375 female anopheline specimens with ten species identified using morphological keys. Mosquito DNA was analysed for human and bovine blood as well as for Plasmodium falciparum and Plasmodium vivax infection.

resultsHuman host feeding was confirmed in Anopheles stephensi (30 %), Anopheles subpictus (27 %), Anopheles jamesii (22 %), Anopheles annularis (26 %), and Anopheles nigerrimus (16 %). In contrast, Anopheles vagus, Anopheles barbirostris, Anopheles tessellates, Anopheles umbrosus and Anopheles karwari specimens were negative for human blood. Importantly, An. subpictus, which was considered a non-vector in Goa and Western India, was found to be a dominant vector in terms of both total number of mosquitoes collected as well as Plasmodium carriage. Plasmodium infections were detected in 14 An. subpictus (2.8 %), while the traditional vector, An. stephensi, showed seven total infections, two of which were in the salivary glands. Of the 14 An. subpictus infections, nested PCR demonstrated three Plasmodium infections in the salivary glands: one P. vivax and two mixed infections of P. falciparum and P. vivax. In addition, ten gut infections (one P. vivax, six P. falciparum and three mixed infections) were seen in An. subpictus. Longitudinal mosquito collections pointed to a bimodal annual appearance of An. subpictus to maintain a perennial malaria transmission cycle of both P. vivax and P. falciparum in Goa.

Indexed as

AnimalsAnophelesFemaleHumansIndiaInsect VectorsMalaria, FalciparumMalaria, VivaxMalePlasmodium falciparumPlasmodium vivaxSeasons

Identifiers

PMID26919828
PMCPMC4769513
OpenAlexW2275975026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.