ArticlePloS one2016
Morpho-Physiological and Proteome Level Responses to Cadmium Stress in Sorghum.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 86 citations in OpenAlex.
- Physiological and Proteomic Analysis of Sorghum Bicolor Seedling Leaves Reveals Molecular Responses to PEG-Induced Drought Stress.Plants (Basel, Switzerland) · 2026Article
- Physio-biochemical and transcriptomic analysis reveals underlying mechanism of Cys-induced amelioration of Cd toxicity in maize.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Transcriptome Proffling, Physiological and Biochemical Analyses Reveal Comprehensive Insights into Cadmium Stress inPlants (Basel, Switzerland) · 2024Article
- Leveraging multi-omics tools to comprehend responses and tolerance mechanisms of heavy metals in crop plants.Functional & integrative genomics · 2024Review
- Integrated transcriptome and metabolomics analyses revealed key functional genes in Canna indica under Cr stress.Scientific reports · 2024Article
- Review
- Ameliorating the effects of multiple stresses on agronomic traits in crops: modern biotechnological and omics approaches.Molecular biology reports · 2023Review
- Effects of Climate Change and Drought Tolerance on Maize Growth.Plants (Basel, Switzerland) · 2023Review
- A novel biochar-based composite hydrogel for removing heavy metals in water and alleviating cadmium stress in tobacco seedlings.Scientific reports · 2023Article
- Transcriptomic Changes Induced by Low and High Concentrations of Heavy Metal Exposure inToxics · 2023Article
- Integration of transcriptome and metabolome analyses reveals sorghum roots responding to cadmium stress through regulation of the flavonoid biosynthesis pathway.Frontiers in plant science · 2023Article
- Understanding the Phytoremediation Mechanisms of Potentially Toxic Elements: A Proteomic Overview of Recent Advances.Frontiers in plant science · 2022Review
- Omics for the Improvement of Abiotic, Biotic, and Agronomic Traits in Major Cereal Crops: Applications, Challenges, and Prospects.Plants (Basel, Switzerland) · 2021Review
- Label-free quantitative proteomics of Sorghum bicolor reveals the proteins strengthening plant defense against insect pest Chilo partellus.Proteome science · 2021Article
- Omics-Facilitated Crop Improvement for Climate Resilience and Superior Nutritive Value.Frontiers in plant science · 2021Review
- Physiological and Differential Proteomic Analyses of Imitation Drought Stress Response inInternational journal of molecular sciences · 2020Article
- Review
- Quantitative proteomic analysis of tomato genotypes with differential cadmium tolerance.Environmental science and pollution research international · 2019Article
- Morpho-Physiological and Proteomic Analyses ofPlants (Basel, Switzerland) · 2019Article
- Biochemical, molecular, and elemental profiling of Withania somnifera L. with response to zinc stress.Environmental science and pollution research international · 2019Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cadmium (Cd) stress may cause serious morphological and physiological abnormalities in addition to altering the proteome in plants. The present study was performed to explore Cd-induced morpho-physiological alterations and their potential associated mechanisms in Sorghum bicolor leaves at the protein level. Ten-day-old sorghum seedlings were exposed to different concentrations (0, 100, and 150 μM) of CdCl2, and different morpho-physiological responses were recorded. The effects of Cd exposure on protein expression patterns in S. bicolor were investigated using two-dimensional gel electrophoresis (2-DE) in samples derived from the leaves of both control and Cd-treated seedlings. The observed morphological changes revealed that the plants treated with Cd displayed dramatically altered shoot lengths, fresh weights and relative water content. In addition, the concentration of Cd was markedly increased by treatment with Cd, and the amount of Cd taken up by the shoots was significantly and directly correlated with the applied concentration of Cd. Using the 2-DE method, a total of 33 differentially expressed protein spots were analyzed using MALDI-TOF/TOF MS. Of these, treatment with Cd resulted in significant increases in 15 proteins and decreases in 18 proteins. Major changes were absorbed in the levels of proteins known to be involved in carbohydrate metabolism, transcriptional regulation, translation and stress responses. Proteomic results revealed that Cd stress had an inhibitory effect on carbon fixation, ATP production and the regulation of protein synthesis. Our study provides insights into the integrated molecular mechanisms involved in responses to Cd and the effects of Cd on the growth and physiological characteristics of sorghum seedlings. We have aimed to provide a reference describing the mechanisms involved in heavy metal damage to plants.
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