Evidence map›Paper›PMID 26918798›Full record

ArticleSurgical infections2016

Renewed Interest in Acute Appendicitis: Are Antibiotics Non-Inferior to Surgery or Possibly Clinically Superior? What Is Long-Term Follow-Up and Natural Evolution of Appendicitis Treated Conservatively with "Antibiotics First"?

Salomone Di Saverio, Massimo Sartelli, Fausto Catena, Arianna Birindelli, Gregorio Tugnoli

Registry-linked trialAbstract readLetterComment
PubMed Publisher
In one paragraph

Article in Surgical infections, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03080103 (A Prospective Non-randomized Controlled, Multicenter, Multidisciplinary Trial Comparing Appendectomy and Conservative Treatment for Patients With Uncomplicated Acute Appendicitis), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03080103 completednot on this mapstarted 2017, after this paper: background citation

A Prospective Non-randomized Controlled, Multicenter, Multidisciplinary Trial Comparing Appendectomy and Conservative Treatment for Patients With Uncomplicated Acute Appendicitis (the ACTUAA STUDY).

TypeobservationalSponsorMauro PoddaRan2017 to 2019Enrolled300ConditionsAcute Appendicitis, Appendicitis Recurrent, Appendectomy, Antibiotic TherapyArmsLaparoscopic or Open appendectomy, Antibiotic-first therapy
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Salomone Di Saverio1 Department of Surgery, Maggiore Hospital-Bologna Local Health District , Bologna, Italy .
Massimo Sartelli3 Department of Surgery, Macerata Hospital , Macerata, Italy .
Fausto Catena4 Emergency and Trauma Surgery Department, Maggiore Hospital of Parma , Parma, Italy .
Arianna Birindelli1 Department of Surgery, Maggiore Hospital-Bologna Local Health District , Bologna, Italy .
Gregorio Tugnoli1 Department of Surgery, Maggiore Hospital-Bologna Local Health District , Bologna, Italy .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute DiseaseAnti-Bacterial AgentsAppendectomyAppendicitisFollow-Up StudiesHumansAnti-Bacterial Agents

Identifiers

PMID26918798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.