ArticleNeurology. Clinical practice2016
Mechanisms and outcomes of stroke during pregnancy and the postpartum period: A cross-sectional study.
Article in Neurology. Clinical practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Spontaneous Intracranial Hemorrhage in Pregnancy: A Systematic Review of the Literature.Neurocritical care · 2019Pooled it
- A Population-Based Study of Posterior Reversible Encephalopathy Syndrome and Reversible Cerebral Vasoconstriction Syndrome During Pregnancy and Puerperium.European journal of neurology · 2026Article
- Association between preeclampsia and reversible cerebral vasoconstriction syndrome: A case-control study.Pregnancy (Hoboken, N.J.) · 2026Article
- Incidence, predictors, types and outcome of Post-Partum stroke: A population based study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Article
- Comparison of Stroke Recurrence, Cardiovascular Events, and Death Among Patients With Pregnancy-Associated vs Non-Pregnancy-Associated Stroke.JAMA network open · 2023Article
- Stroke in Women: A Review Focused on Epidemiology, Risk Factors, and Outcomes.Journal of stroke · 2023Review
- Uncommon Female-Predominant Etiologies of Cryptogenic Stroke.Frontiers in neurology · 2022Review
- Postpartum Acute Basilar Artery Occlusion Secondary to Vertebral Artery Dissection. Case Report and Literature Review.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2021Article
- Maternal Stroke: A Call for Action.Circulation · 2021Review
- Cerebrovascular disease in pregnancy and puerperium: perspectives from neuroradiologists.Quantitative imaging in medicine and surgery · 2021Review
- Postpartum Hypertension.Current hypertension reports · 2020Review
- Stroke in Pregnancy: A Focused Update.Anesthesia and analgesia · 2020Review
- Ischemic stroke and cerebral venous sinus thrombosis in pregnancy.Handbook of clinical neurology · 2020Review
- Maternal Stroke: an Update.Current atherosclerosis reports · 2019Review
- Sex differences in stroke: Challenges and opportunities.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2018Review
- Causes and Treatment of Acute Ischemic Stroke During Pregnancy.Current treatment options in neurology · 2018Review
- Pregnancy-Associated Stroke.Journal of midwifery & women's health · 2018Review
- Stroke in women - from evidence to inequalities.Nature reviews. Neurology · 2017Review
- Hemolysis, Elevated Liver Enzymes, and Low Platelets, Severe Fetal Growth Restriction, Postpartum Subarachnoid Hemorrhage, and Craniotomy: A Rare Case Report and Systematic Review.Case reports in obstetrics and gynecology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPregnancy-associated stroke remains incompletely characterized because of the rarity of these potentially devastating events. We investigated whether mechanism and outcome of ischemic pathophysiology stroke differ between young pregnant and nonpregnant women.
methodsWe identified 135 consecutive women ages 18-40 years admitted to our center from January 2008 through June 2014 with ischemic stroke, TIA, cerebral venous thrombosis, or nonaneurysmal subarachnoid hemorrhage due to reversible cerebral vasoconstriction syndrome (RCVS). We reviewed charts for pregnancy status, demographics, medical comorbidities, stroke severity, etiology, and discharge outcomes.
resultsThere were 33 women with pregnancy-associated stroke (PAS) and 102 with non-pregnancy-associated stroke (NPAS). Among women with PAS, 73% of strokes occurred postpartum. In the PAS group, the most common cause of cerebrovascular events was RCVS (n = 12), 11 postpartum and 4 in women with preeclampsia. There were no significant differences between the groups in demographics. Women with PAS were less likely to have vascular risk factors such as hyperlipidemia and history of thromboembolism but more likely to have cerebral venous thromboses (21% vs 7%,
conclusionCompared with nonpregnant women of the same age group, women with PAS had fewer vascular risk factors. Cerebral venous thrombosis and RCVS were more common in PAS, most of which occurred postpartum. These results provide further evidence for the unique pathophysiology of pregnancy-related stroke, raising important questions for future investigation.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.