Evidence map›Paper›PMID 26918180›Full record

ReviewF1000Research2016

Recent Understandings of Pet Allergies.

Dennis Ownby, Christine Cole Johnson

Abstract readReview
In one paragraph

Review in F1000Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. BORN TO WHEEZE OR LEARNED WHEN WE WERE YOUNG: MATERNAL AND ENVIRONMENTAL FACTORS INFLUENCE ATOPIC RISK.Transactions of the American Clinical and Climatological Association · 2023
    Article
  2. Best Practice Standards in Animal-Assisted Interventions: How theAnimals : an open access journal from MDPI · 2020
    Article
  3. Article
  4. Bedroom Allergen Exposure Beyond House Dust Mites.Current allergy and asthma reports · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dennis OwnbyGeorgia Regents University, Augusta, GA, USA.
Christine Cole JohnsonDepartment of Public Health Sciences, Henry Ford Health System, Detroit, MI, USA.

Funding

The Effect of Dog-Keeping and the Intestinal Microbiota on Immune DevelopmentP01AI089473 · NIAID · HENRY FORD HEALTH SYSTEM · PI OWNBY, DENNIS R · 2012 to 2024
$25.7M
NIAID NIH HHS P01 AI089473
6 · The paper itself

Abstract

Allergic reactions to pets have been recognized for at least a hundred years. Yet our understanding of the effects of all of the interactions between pet exposures and human immune responses continues to grow. Allergists, epidemiologists, and immunologists have spent years trying to better understand how exposures to pet allergens lead to allergic sensitization (the production of allergen-specific immunoglobulin class E [IgE] antibodies) and subsequent allergic disease. A major new development in this understanding is the recognition that pet exposures consist of not only allergen exposures but also changes in microbial exposures. Exposures to certain pet-associated microbes, especially in the neonatal period, appear to be able to dramatically alter how a child's immune system develops and this in turn reduces the risk of allergic sensitization and disease. An exciting challenge in the next few years will be to see whether these changes can be developed into a realistic preventative strategy with the expectation of significantly reducing allergic disease, especially asthma.

Indexed as

Allergic reactionsallergic sensitizationIgE antibodiesPet Allergies

Identifiers

PMID26918180
PMCPMC4755411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.