ReviewF1000Research2015
Primordial Germ Cell Specification and Migration.
Review in F1000Research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Germline organoids develop in vitro from embryonic Taeniopygia guttata (zebra finch) cultures.Scientific reports · 2026Article
- Mitochondrial curation for the next generation.Current opinion in genetics & development · 2025Review
- Clonal analysis reveals differential PGC contributions to the early germline and ovarian reserve.bioRxiv : the preprint server for biology · 2025Article
- Induced formation of primordial germ cells from zebrafish blastomeres by germplasm factors.Nature communications · 2023Article
- Germline/soma distinction ineLife · 2023Article
- 3D cellular morphometrics of ovule primordium development inFrontiers in plant science · 2023Article
- A Germline-Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Early Gonadal Development and Sex Determination in Mammal.International journal of molecular sciences · 2022Review
- Sinhcaf-dependent histone deacetylation is essential for primordial germ cell specification.EMBO reports · 2022Article
- Bloom syndrome helicase contributes to germ line development and longevity in zebrafish.Cell death & disease · 2022Article
- Proper Balance of Small GTPaseInternational journal of molecular sciences · 2021Article
- The initial expansion of the C. elegans syncytial germ line is coupled to incomplete primordial germ cell cytokinesis.Development (Cambridge, England) · 2021Article
- Article
- Zebrafish dazl regulates cystogenesis and germline stem cell specification during the primordial germ cell to germline stem cell transition.Development (Cambridge, England) · 2021Article
- Tools to Image Germplasm Dynamics During Early Zebrafish Development.Frontiers in cell and developmental biology · 2021Article
- Why isn't sex optional? Stem-cell competition, loss of regenerative capacity, and cancer in metazoan evolution.Communicative & integrative biology · 2020Review
- Human Ovarian Cortex biobanking: A Fascinating Resource for Fertility Preservation in Cancer.International journal of molecular sciences · 2020Review
- A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka.PLoS biology · 2019Article
- Heterogeneity of primordial germ cells.Current topics in developmental biology · 2019Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Primordial germ cells are the progenitor cells that give rise to the gametes. In some animals, the germline is induced by zygotic transcription factors, whereas in others, primordial germ cell specification occurs via inheritance of maternally provided gene products known as germ plasm. Once specified, the primordial germ cells of some animals must acquire motility and migrate to the gonad in order to survive. In all animals examined, perinuclear structures called germ granules form within germ cells. This review focuses on some of the recent studies, conducted by several groups using diverse systems, from invertebrates to vertebrates, which have provided mechanistic insight into the molecular regulation of germ cell specification and migration.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.