Inherited DDX41 mutations: 11 genes and counting.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. MDS/AML-associated DDX41 helicase facilitates homologous recombination repair by potentially resolving R-loops.Nucleic acids research · 2026
   Article
2. How I diagnose myeloid neoplasms with germline predisposition.American journal of clinical pathology · 2023
   Article
3. Assessment of technical heterogeneity among diagnostic tests to detect germline risk variants for hematopoietic malignancies.Genetics in medicine : official journal of the American College of Medical Genetics · 2021
   Article
4. Spliceosomal factor mutations and mis-splicing in MDS.Best practice & research. Clinical haematology · 2020
   Review
5. Nordic Guidelines for Germline Predisposition to Myeloid Neoplasms in Adults: Recommendations for Genetic Diagnosis, Clinical Management and Follow-up.HemaSphere · 2019
   Article
6. Familial predisposition to TP53/complex karyotype MDS and leukemia in DNA repair-deficient xeroderma pigmentosum.Blood · 2019
   Article
7. Hereditary Myelodysplastic Syndrome and Acute Myeloid Leukemia: Diagnosis, Questions, and Controversies.Current hematologic malignancy reports · 2018
   Review
8. Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies.Blood advances · 2018
   Article
9. Re-emergence of acute myeloid leukemia in donor cells following allogeneic transplantation in a family with a germline DDX41 mutation.Leukemia · 2017
   Article
10. Discussing and managing hematologic germ line variants.Hematology. American Society of Hematology. Education Program · 2016
    Review

Corrections and comments

• Comment on
  Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies.2016

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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