Evidence map›Paper›PMID 26917445›Full record

Observational studyAmerican journal of hypertension2016

Achieving Weight Loss and Hypertension Control Among Obese Adults: A US Multidisciplinary Group Practice Observational Study.

Aaron K Ho, Christie M Bartels, Carolyn T Thorpe, Nancy Pandhi, Maureen A Smith, Heather M Johnson

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in American journal of hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 43 citations in OpenAlex.

  1. Overweight-Related Hypertension in Middle-Aged Men Is Linked to Elevated Leptin, TNF-α, IL-6, Cholesterol, and Reduced Testosterone.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Article
  2. Article
  3. Development of a risk prediction score for hypertension incidence using Japanese health checkup data.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Article
  4. Article
  5. Article
  6. Increased Body Mass Index and Hypertension: An Unbreakable Bond.International journal of preventive medicine · 2020
    Article
  7. Review
  8. Article
  9. Observational
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aaron K HoDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA;
Christie M BartelsDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA; Health Innovation Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA;
Carolyn T ThorpeHealth Services Research and Development, Veterans Affairs Pittsburgh Healthcare System , Pittsburgh, Pennsylvania, USA; Department of Pharmacy & Therapeutics, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania, USA;
Nancy PandhiHealth Innovation Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA; Department of Family Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA;
Maureen A SmithHealth Innovation Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA;
Heather M JohnsonDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA; Health Innovation Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA; hm2@medicine.wisc.edu.
University of Wisconsin–Madison · USUniversity of Pittsburgh · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
Identifying and Addressing Barriers to Hypertension Control in Young AdultsK23HL112907 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI JOHNSON, HEATHER M · 2012 to 2016
$845k
Continuity of Care and the Health of Older AdultsK08AG029527 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI PANDHI, NANCY · 2009 to 2013
$669k
Impact of Rheumatologist Communication Upon Managing Cardiovascular Risk in RAK23AR062381 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI BARTELS, CHRISTIE MICHELS · 2012 to 2015
$423k
NCATS NIH HHS UL1 TR000427NCRR NIH HHS UL1 RR025011NHLBI NIH HHS K23 HL112907NIAMS NIH HHS K23 AR062381NIA NIH HHS K08 AG029527
6 · The paper itself

Abstract

backgroundAmong adults with hypertension, obesity independently contributes to cardiovascular disease. Weight loss and hypertension control are critical to reduce cardiovascular events. The purpose of this study was to evaluate rates and predictors of achieving weight loss among adults who achieved hypertension control within 1 year of developing incident hypertension.

methodsRetrospective electronic health record analysis was performed of ≥18 year olds with a body mass index ≥30.0kg/m(2), who received regular primary care from 2008 to 2011 and achieved hypertension control. Exclusions were less than 60 days follow-up, prior hypertension diagnosis, prior antihypertensive prescription, or pregnancy. The primary outcome was clinically significant weight loss (≥5kg); the secondary outcome was modest (2.0-4.9kg) weight loss. Multinomial logistic regression identified predictors of achieving weight loss (≥5 or 2.0-4.9kg) compared to no significant weight loss (<2kg).

resultsOf the 2,906 obese patients who achieved hypertension control, 72% (n = 2,089) did not achieve at least 2.0kg weight loss. Overall, 12% (n = 351) achieved ≥5kg weight loss. Young adults (18-39 year olds; odds ratio (OR): 2.47, 95% confidence interval (CI): 1.63-3.47), middle-aged adults (40-59 year olds; OR: 2.32, 95% CI: 1.59-3.37), and patients prescribed antihypertensive medication (OR: 1.37, 95% CI: 1.07-1.76) were more likely to achieve clinically significant weight loss and hypertension control. Age remained a significant predictor for 2.0-4.9kg weight loss.

conclusionsDespite achieving hypertension control, the majority of obese patients did not achieve clinically significant weight loss. Effective weight loss interventions with dedicated hypertension treatment are needed to decrease cardiovascular events in this high-risk population.

Indexed as

Weight LossAdultFemaleGroup PracticeHumansHypertensionInterdisciplinary ResearchMaleMiddle AgedObesityRetrospective Studiesblood pressurehypertensionobesityprimary careweight management.

Identifiers

PMID26917445
PMCPMC4941595
OpenAlexW2297055578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.