Evidence map›Paper›PMID 26917406›Full record

ArticleScientific reports2016

Societal Burden and Correlates of Acute Gastroenteritis in Families with Preschool Children.

Lapo Mughini-Gras, Roan Pijnacker, Moniek Heusinkveld, Remko Enserink, Rody Zuidema, Erwin Duizer, Titia Kortbeek, Wilfrid van Pelt

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Prevalence, Serotypes and Antimicrobial Resistance ofInfection and drug resistance · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Acute Infectious Gastroenteritis in Infancy and Childhood.Deutsches Arzteblatt international · 2020
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Potential causative agents of acute gastroenteritis in households with preschool children: prevalence, risk factors, clinical relevance and household transmission.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lapo Mughini-GrasNational Institute for Public Health and the Environment (RIVM), Centre for Infectious Disease Control (CIb), PO Box 1, 3720 BA Bilthoven, the Netherlands.
Roan PijnackerNational Institute for Public Health and the Environment (RIVM), Centre for Infectious Disease Control (CIb), PO Box 1, 3720 BA Bilthoven, the Netherlands.
Moniek HeusinkveldNational Institute for Public Health and the Environment (RIVM), Centre for Infectious Disease Control (CIb), PO Box 1, 3720 BA Bilthoven, the Netherlands.
Remko EnserinkNational Institute for Public Health and the Environment (RIVM), Centre for Infectious Disease Control (CIb), PO Box 1, 3720 BA Bilthoven, the Netherlands.
Rody ZuidemaNational Institute for Public Health and the Environment (RIVM), Centre for Infectious Disease Control (CIb), PO Box 1, 3720 BA Bilthoven, the Netherlands.
Erwin DuizerNational Institute for Public Health and the Environment (RIVM), Centre for Infectious Disease Control (CIb), PO Box 1, 3720 BA Bilthoven, the Netherlands.
Titia KortbeekNational Institute for Public Health and the Environment (RIVM), Centre for Infectious Disease Control (CIb), PO Box 1, 3720 BA Bilthoven, the Netherlands.
Wilfrid van PeltNational Institute for Public Health and the Environment (RIVM), Centre for Infectious Disease Control (CIb), PO Box 1, 3720 BA Bilthoven, the Netherlands.
National Institute for Public Health and the Environment · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal infection morbidity remains high amongst preschool children in developed countries. We investigated the societal burden (incidence, healthcare utilization, and productivity loss) and correlates of acute gastroenteritis (AGE) in families with preschoolers. Monthly for 25 months, 2000 families reported AGE symptoms and related care, productivity loss, and risk exposures for one preschooler and one parent. Amongst 8768 child-parent pairs enrolled, 7.3% parents and 17.4% children experienced AGE (0.95 episodes/parent-year and 2.25 episodes/child-year). Healthcare utilization was 18.3% (children) and 8.6% (parents), with 1.6% children hospitalized. Work absenteeism was 55.6% (median 1.5 days) and day-care absenteeism was 26.2% (median 1 day). Besides chronic enteropathies, antacid use, non-breastfeeding, and toddling age, risk factors for childhood AGE were having developmental disabilities, parental occupation in healthcare, multiple siblings, single-parent families, and ≤ 12-month day-care attendance. Risk factors for parental AGE were female gender, having multiple or developmentally-disabled day-care-attending children, antimicrobial use, and poor food-handling practices. Parents of AGE-affected children had a concurrent 4-fold increased AGE risk. We concluded that AGE-causing agents spread widely in families with preschool children, causing high healthcare-seeking behaviours and productivity losses. Modifiable risk factors provide targets for AGE-reducing initiatives. Children may acquire some immunity to AGE after one year of day-care attendance.

Indexed as

AbsenteeismAntacidsChild Day Care CentersChild, PreschoolCross-Sectional StudiesDelivery of Health CareFemaleGastroenteritisHumansMaleNetherlandsRetrospective StudiesRisk FactorsSurveys and QuestionnairesAntacids

Identifiers

PMID26917406
PMCPMC4768267
OpenAlexW2297844305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.