Evidence map›Paper›PMID 26916657›Full record

Trial reportInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2016

Application of low injection rate and low contrast agent dose in three-dimensional rotational digital subtraction angiography of the intracranial aneurysm.

Zhimei Gao, Yongming Zeng, Jingkun Sun, Jingjie Yang, Yang Zhou, Mi Zhou, Tingni Song

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Optimizing contrast-enhanced cone-beam CT protocol to facilitate simultaneous visualization of neurovascular pathologies and surrounding structures of interest.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2019
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhimei GaoThe First Affiliated Hospital of Chongqing Medical University, China.
Yongming ZengThe First Affiliated Hospital of Chongqing Medical University, China zeng-ym@hotmail.com.
Jingkun SunThe First Affiliated Hospital of Chongqing Medical University, China.
Jingjie YangThe First Affiliated Hospital of Chongqing Medical University, China.
Yang ZhouThe First Affiliated Hospital of Chongqing Medical University, China.
Mi ZhouThe First Affiliated Hospital of Chongqing Medical University, China.
Tingni SongThe First Affiliated Hospital of Chongqing Medical University, China.
Chongqing Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this article is to explore the feasibility of low injection rate and low contrast agent dose in three-dimensional rotational digital subtraction angiography (3D DSA) of the intracranial aneurysm. MATERIALS AND

methodsFifty-one patients with suspected intracranial aneurysms were included. The catheter tip was kept within the internal carotid artery at the epistropheus level. Patients were divided into three groups randomly according to injection rate: group A (1.5 ml/s, n = 18), group B (2.0 ml/s, n = 18), and group C (3.0 ml/s, n = 15). The noise, signal-to-noise ratio (SNR), and carrier-to-noise ratio (CNR) of C2, C6, M1, and A1 segments were calculated. The continuous subtraction images and reconstructed images were evaluated by two technicians.

resultsNo significant differences were found in noise between groups A and B, and groups A and C. Significant differences were found in the SNR and CNR of M1 and A1 segments between groups A and B, and groups B and C, but for C2 and C6 segments, they were not significant. Significant differences were found in the SNR and CNR of all segments between groups A and C. Significant differences were found in the contrast agent dose between all three groups. No significant differences were found in scores evaluated by two physicians between the three groups.

conclusionThe personalized injection protocol of low injection rate and low contrast agent dose in 3D DSA of the intracranial aneurysm is feasible. The application of this protocol can reduce the dose of iodine and obtain satisfactory images.

Indexed as

AdolescentAdultAgedAngiography, Digital SubtractionCarotid Artery, InternalCerebral AngiographyContrast MediaDouble-Blind MethodFeasibility StudiesFemaleHumansImaging, Three-DimensionalInjections, Intra-ArterialIntracranial AneurysmIohexolMaleContrast MediaIohexoliopromidecerebral vascularcontrast mediumDigital subtraction angiographyimaging quality

Identifiers

PMID26916657
PMCPMC4984369
OpenAlexW2340709450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.