SynthesisAmerican journal of preventive medicine2016
Interventions for Childhood Obesity in the First 1,000 Days A Systematic Review.
Synthesis in American journal of preventive medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 187 papers, 20 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cluster Randomised Controlled Feasibility Study of HENRY; a Community Based Intervention Aimed at Reducing School Entry Obesity Rates
INFANT HEALTH- Supporting Infants' Mental Health and Healthy Weight Development Through Community Health Nurses' Promoting Sensitive Parenting
Evaluation of a Tailored Multicomponent Early Intervention for Childhood Obesity Prevention in Vulnerable Families (Bambú Project): Randomized Controlled Trial With a Hybrid Type 1 Effectiveness-implementation Design
Who cites it
187 citing papers in PubMed, 20 syntheses or guidelines pooled it, 379 citations in OpenAlex.
- Digital Interventions Targeting Parents to Improve Early Childhood Movement, Nutrition, and Sleep Behaviors: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Cardiovascular Prevention in Children, Adolescents, and Young Adults. A Call-to-Action of the Italian Societies of Pediatrics (SIP), Hypertension (SIIA), Study of Atherosclerosis (SISA), and Cardiovascular Prevention (SIPREC).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Guideline
- Risk Factors in the First 1000 Days of Life Associated With Childhood Obesity: A Systematic Review and Risk Factor Quality Assessment.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Public health interventions for the prevention and management of overweight and obesity in children and adolescents: a rapid review.Frontiers in public health · 2026Pooled it
- Parental engagement with complementary feeding information in the United Kingdom: A qualitative evidence synthesis.Maternal & child nutrition · 2023Pooled it
- Adoption, implementation, and sustainability of early childhood feeding, nutrition and active play interventions in real-world settings: a systematic review.The international journal of behavioral nutrition and physical activity · 2023Pooled it
- The effectiveness of interventions during the first 1,000 days to improve energy balance-related behaviors or prevent overweight/obesity in children from socio-economically disadvantaged families of high-income countries: a systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Pooled it
- Food insecurity and its socioeconomic and health determinants in pregnant women and mothers of children under 2 years of age, during the COVID-19 pandemic: A systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Interventions in the first 1000 days to prevent childhood obesity: a systematic review and quantitative content analysis.BMC public health · 2022Pooled it
- Cultural adaptations of obesity-related behavioral prevention interventions in early childhood: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022Pooled it
- Pediatric Obesity Prevention and Treatment Among Hispanics: A Systematic Review and Meta-Analysis.American journal of preventive medicine · 2022Pooled it
- Addressing obesity in the first 1000 days in high risk infants: Systematic review.Maternal & child nutrition · 2021Pooled it
- Pooled it
- Interventions that prevent or reduce obesity in children from birth to five years of age: A systematic review.Journal of child health care : for professionals working with children in the hospital and community · 2021Pooled it
- Associations between lifestyle interventions during pregnancy and childhood weight and growth: a systematic review and meta-analysis.The international journal of behavioral nutrition and physical activity · 2021Pooled it
- Clinical audit in the pediatric primary care office and overweight prevention in toddlers.BMC pediatrics · 2020Pooled it
- A Systematic Review of Methods, Study Quality, and Results of Economic Evaluation for Childhood and Adolescent Obesity Intervention.International journal of environmental research and public health · 2019Pooled it
- Health professional-delivered obesity prevention interventions during the first 1,000 days: A systematic review of external validity reporting.HRB open research · 2019Pooled it
- Developing a core outcome set for childhood obesity prevention: A systematic review.Maternal & child nutrition · 2019Pooled it
- Can antenatal diet and lifestyle interventions influence childhood obesity? A systematic review.Maternal & child nutrition · 2018Pooled it
127 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
contextThe "first 1,000 days"-conception through age 24 months-are critical for the development and prevention of childhood obesity. This study systematically reviews existing and ongoing interventions during this period, identifies gaps in current research, and discusses conceptual frameworks and opportunities for future interventions. EVIDENCE ACQUISITION: PubMed, Embase, Web of Science, and ClinicalTrials.gov were searched to identify completed and ongoing interventions implemented during pregnancy through age 24 months that aimed to prevent overweight/obesity between ages 6 months and 18 years. English-language, controlled interventions published between January 1, 1980 and December 12, 2014, were analyzed between December 13, 2014 and March 15, 2015. EVIDENCE SYNTHESIS: Of 34 completed studies from 26 unique identified interventions, nine were effective. Effective interventions focused on individual- or family-level behavior changes through home visits, individual counseling or group sessions in clinical settings, a combination of home and group visits in a community setting, and using hydrolyzed protein formula. Protein-enriched formula increased childhood obesity risk. Forty-seven ongoing interventions were identified. Across completed and ongoing interventions, the majority target individual- or family-level changes, many are conducted in clinical settings, and few target early-life systems and policies that may impact childhood obesity.
conclusionsObesity interventions may have the greatest preventive effect if begun early in life. Yet, few effective interventions in the first 1,000 days exist, and many target individual-level behaviors of parents and infants. Interventions that operate at systems levels and are grounded in salient conceptual frameworks hold promise for improving future models of early-life obesity prevention.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.