Evidence map›Paper›PMID 26915895›Full record

ArticleThe neuroradiology journal2016

Perinatal MRI diffusivity is related to early assessment of motor performance in preterm neonates.

Riccardo Navarra, Carlo Sestieri, Emanuela Conte, Rita Salomone, Peter A Mattei, Gian L Romani, Sergio Domizio, Massimo Caulo

Abstract read
In one paragraph

Article in The neuroradiology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Riccardo NavarraDepartment of Neuroscience and Imaging, G d'Annunzio University, Chieti, Italy Institute of Advanced Biomedical Technologies (ITAB), G d'Annunzio University, Chieti, Italy r.navarra@itab.unich.it.
Carlo SestieriDepartment of Neuroscience and Imaging, G d'Annunzio University, Chieti, Italy Institute of Advanced Biomedical Technologies (ITAB), G d'Annunzio University, Chieti, Italy.
Emanuela ConteDepartment of Neonatology, San Salvatore Hospital, L'Aquila, Italy.
Rita SalomoneDepartment of Pediatrics and Neonatology, G d'Annunzio University, Chieti, Italy.
Peter A MatteiDepartment of Medicine and Aging Sciences, G d'Annunzio University, Chieti, Italy.
Gian L RomaniDepartment of Neuroscience and Imaging, G d'Annunzio University, Chieti, Italy Institute of Advanced Biomedical Technologies (ITAB), G d'Annunzio University, Chieti, Italy.
Sergio DomizioDepartment of Pediatrics and Neonatology, G d'Annunzio University, Chieti, Italy.
Massimo CauloDepartment of Neuroscience and Imaging, G d'Annunzio University, Chieti, Italy Institute of Advanced Biomedical Technologies (ITAB), G d'Annunzio University, Chieti, Italy.
University of Chieti-Pescara · ITSan Salvatore Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preterm neonates represent a high-risk population for abnormal neuropsychological development. But presently, an accurate method for identifying those at risk is not available. This study evaluated the association between the microstructural organization measured with Diffusion Tensor Imaging (DTI) in term-corrected preterm neonates and subsequent motor performance. Fractional anisotropy (FA), axial diffusion (AD), mean diffusivity (MD) and radial diffusivity (RD) were determined in two regions of interest (ROIs) corresponding to the posterior limb of the internal capsule (PLIC) and cortico-spinal tract (CST). The Griffiths Mental Developmental Scales (GMDS) were longitudinally administered at 3, 6 and 15 months; and correlations between the metrics of diffusivity and the motor subscale of the GMDS were assessed using the Spearman correlation. A statistically significant negative correlation was observed between the AD of PLIC of the left hemisphere and the 3-month GMDS Locomotor Subscale. These results suggested that AD is a valid indicator of the stage of maturation of the motor pathway in preterm neonates, but not of later motor outcome.

Indexed as

Diffusion Tensor ImagingAnalysis of VarianceAnisotropyBrainFemaleFollow-Up StudiesGestational AgeHumansInfantInfant, NewbornMagnetic Resonance ImagingMaleMotor DisordersPremature BirthStatistics as TopicAxial diffusiondiffusion tensor imagingfetal developmentmotor outcomemotor systemneurological developmentneurological indicatorspreterm neonates

Identifiers

PMID26915895
PMCPMC4978313
OpenAlexW2306459643

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.