Trial reportJournal of the European Academy of Dermatology and Venereology : JEADV2016
Prevalence of rosacea in the general population of Germany and Russia - The RISE study.
Trial report in Journal of the European Academy of Dermatology and Venereology : JEADV, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06952517 (Efficacy and Safety of Topical Clascoterone Cream 1% in Patients With Facial Acneiform Rosacea), which is not on this map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy and Safety of Topical Clascoterone Cream 1% in Patients With Facial Acneiform Rosacea
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 143 citations in OpenAlex.
- [Rosacea-the updated S2k guideline].Dermatologie (Heidelberg, Germany) · 2023Guideline
- Laser-Based Therapies in Rosacea: A Comprehensive Review of Mechanisms, Clinical Efficacy, and Future Directions.Journal of clinical medicine · 2026Review
- Exploring Factors, Comorbidities, Quality of Life (DLQI), and Depression (PHQ-9) in Rosacea Patients: A Comprehensive Analysis.Journal of cosmetic dermatology · 2025Observational
- Differences in the Clinical Characteristics of Male Patients With Different Ages of Rosacea: A Retrospective Study of 215 Male Outpatients.Journal of cosmetic dermatology · 2025Article
- Causal relationship between plasma lipidome and rosacea: a Mendelian randomization analysis.Frontiers in endocrinology · 2025Article
- Topical Drug Treatment of Rosacea in Switzerland: A Descriptive Study Using Swiss Claims Data.Dermatology (Basel, Switzerland) · 2025Article
- Rosacea and treatment with retinoids: a systematic review and meta-analysis.Therapeutic advances in chronic disease · 2025Review
- Poly-d,l-Lactic Acid Via Transdermal Microjet Drug Delivery for Treating Rosacea in Asian Patients.Journal of cosmetic dermatology · 2024Article
- Efficacy and Safety of Microencapsulated Benzoyl Peroxide Cream, 5%, in Papulopustular Rosacea in Elderly Patients: Post-hoc Analysis of Results from Two Randomized, Phase III, Vehicle-controlled Trials.The Journal of clinical and aesthetic dermatology · 2024Article
- The role of vitamins and nutrients in rosacea.Archives of dermatological research · 2024Review
- Topical 10% Tranexamic Acid with and without Microneedling in the Treatment of Erythematotelangiectatic Rosacea: A Split-face Comparative Study.The Journal of clinical and aesthetic dermatology · 2024Article
- Diagnosing and Treating Rosacea in Skin of Color Patients.The Journal of clinical and aesthetic dermatology · 2023Article
- Rosacea Topical Treatment and Care: From Traditional to New Drug Delivery Systems.Molecular pharmaceutics · 2023Review
- Efficacy and Safety of Microencapsulated Benzoyl Peroxide Cream, 5%, in Rosacea: Results From Two Phase III, Randomized, Vehicle-Controlled Trials.The Journal of clinical and aesthetic dermatology · 2023Article
- Clinicopathological Survey of 204 Rosacea Patients Regarding Rosacea Subgroups and Severity.Dermatology practical & conceptual · 2023Article
- Association between the Treatment of Rosacea and Eradication ofAdvanced biomedical research · 2023Article
- Prevalence of most common skin diseases in Europe: a population-based study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022Article
- Patient Visits and Prescribing Patterns Associated with Rosacea in Korea: A Real-World Retrospective Study Based on Electronic Medical Records.Journal of clinical medicine · 2022Article
- A Cross-Sectional Study on the Relationship Between Rosacea Severity and Quality of Life or Psychological State.Clinical, cosmetic and investigational dermatology · 2022Article
- Clinical characteristics of combined rosacea and migraine.Frontiers in medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is an unmet need for general population-based epidemiological data on rosacea based on contemporary diagnostic criteria and validated population survey methodology.
objectiveTo evaluate the prevalence of rosacea in the general population of Germany and Russia.
methodsGeneral population screening was conducted in 9-10 cities per country to ensure adequate geographic representation. In Part I of this two-phase study, screening of a representative sample of the general population (every fifth person or every fifth door using a fixed-step procedure on a random route sample) was expedited with use of a questionnaire and algorithm based on current diagnostic criteria for rosacea. Of the subjects that screened positive in the initial phase, a randomly selected sample (every third subject) t`hen underwent diagnostic confirmation by a dermatologist in Part II.
resultsA total of 3052 and 3013 subjects (aged 18-65 years) were screened in Germany and Russia respectively. Rosacea prevalence was 12.3% [95%CI, 10.2-14.4] in Germany and 5.0% [95%CI, 2.8-7.2] in Russia. The profile of subjects with rosacea (75% women; mean age of 40 years; mainly skin phototype II or III, majority of subjects with sensitive facial skin) and subtype distribution were similar. Overall, 18% of subjects diagnosed with rosacea were aged 18-30 years. Over 80% were not previously diagnosed. Within the previous year, 47.5% of subjects had received no rosacea care and 23.7% had received topical and/or systemic drugs. Over one-third (35% Germany, 43% Russia) of rosacea subjects reported a moderate to severe adverse impact on quality of life.
conclusionRosacea is highly prevalent in Germany (12.3%) and Russia (5.0%). The demographic profile of rosacea subjects was similar between countries and the majority were previously undiagnosed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.