ReviewJournal of stroke2016
Ischemic Stroke after Heart Transplantation.
Review in Journal of stroke, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Stroke after lung transplantation: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Homocysteine is associated with higher risks of ischemic stroke: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Characteristics and outcomes of thromboembolism following cardiac transplant: a multi-institutional retrospective study.Research and practice in thrombosis and haemostasis · 2025Article
- Association of stroke and mortality among patients receiving heart transplantation-a nationwide study.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Artificial Intelligence Approaches for Predicting the Risks of Durable Mechanical Circulatory Support Therapy and Cardiac Transplantation.Journal of clinical medicine · 2024Review
- Microvesicular Steatosis and Severe Cardiac Allograft Dysfunction.Transplantation direct · 2022Article
- A Nomogram for Predicting Patent Foramen Ovale-Related Stroke Recurrence.Frontiers in neurology · 2022Article
- Anterior Circulation Acute Ischemic Stroke in the Plateau of China: Risk Factors and Clinical Characteristics.Frontiers in neurology · 2022Article
- Trends, risk factors, and outcomes of post-operative stroke after heart transplantation: an analysis of the UNOS database.ESC heart failure · 2021Article
- Editorial: Cardiorespiratory Coupling-Novel Insights for Integrative Biomedicine.Frontiers in neuroscience · 2021Article
- Posterior Reversible Encephalopathy Syndrome Associated with Tacrolimus in Cardiac Transplantation.Case reports in cardiology · 2021Article
- Cerebrovascular risk factors associated with ischemic stroke in a young non-diabetic and non-hypertensive population: a retrospective case-control study.BMC neurology · 2020Article
- Comparison of serum Lp-PLA2 levels in ischemic stroke patients with H-type hypertension or non-H-type hypertension.Journal of clinical laboratory analysis · 2020Article
- Article
- Percutaneous coronary intervention in patients hospitalized for non-ST-elevation myocardial infarction and the risk of postdischarge ischemic stroke at 6-month, 1-year, and 3-year follow-ups.Heart and vessels · 2019Article
- Perioperative stroke and hyperhomocysteinemia: a possible pathogenic link.Korean journal of anesthesiology · 2018Article
- Factor VIIa administration in orthotopic heart transplant recipients and its impact on thromboembolic events and post-transplant outcomes.Journal of thrombosis and thrombolysis · 2018Article
- Postoperative atrial fibrillation and ischemic stroke: The role of homocysteine.European stroke journal · 2018Article
- Perioperative stroke: pathophysiology and management.Korean journal of anesthesiology · 2018Review
- Autonomic Nervous System and Stress to Predict Secondary Ischemic Events after Transient Ischemic Attack or Minor Stroke: Possible Implications of Heart Rate Variability.Frontiers in neurology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebrovascular complications after orthotopic heart transplantation (OHT) are more common in comparison with neurological sequelae subsequent to routine cardiac surgery. Ischemic stroke and transient ischemic attack (TIA) are more common (with an incidence of up to 13%) than intracranial hemorrhage (2.5%). Clinically, ischemic stroke is manifested by the appearance of focal neurologic deficits, although sometimes a stroke may be silent or manifests itself by the appearance of encephalopathy, reflecting a diffuse brain disorder. Ischemic stroke subtypes distribution in perioperative and postoperative period after OHT is very different from classical distribution, with different pathogenic mechanisms. Infact, ischemic stroke may be caused by less common and unusual mechanisms, linked to surgical procedures and to postoperative inflammation, peculiar to this group of patients. However, many strokes (40%) occur without a well-defined etiology (cryptogenic strokes). A silent atrial fibrillation (AF) may play a role in pathogenesis of these strokes and P wave dispersion may represent a predictor of AF. In OHT patients, P wave dispersion correlates with homocysteine plasma levels and hyperhomocysteinemia could play a role in the pathogenesis of these strokes with multiple mechanisms increasing the risk of AF. In conclusion, stroke after heart transplantation represents a complication with considerable impact not only on mortality but also on subsequent poor functional outcome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.