Evidence map›Paper›PMID 26915081›Full record

ArticleMagma (New York, N.Y.)2016

Clinical evaluation of ultra-high-field MRI for three-dimensional visualisation of tumour size in uveal melanoma patients, with direct relevance to treatment planning.

Jan-Willem M Beenakker, Teresa A Ferreira, Karina P Soemarwoto, Stijn W Genders, Wouter M Teeuwisse, Andrew G Webb, Gregorius P M Luyten

Open access · hybridAbstract read
In one paragraph

Article in Magma (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 59 citations in OpenAlex.

  1. Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain.Advanced materials (Deerfield Beach, Fla.) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jan-Willem M BeenakkerDepartment of Radiology, C.J. Gorter Center for High-field MRI, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands. j.w.m.beenakker@lumc.nl.
Teresa A FerreiraDepartment of Radiology, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Karina P SoemarwotoDepartment of Radiology, C.J. Gorter Center for High-field MRI, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Stijn W GendersDepartment of Ophthalmology, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Wouter M TeeuwisseDepartment of Radiology, C.J. Gorter Center for High-field MRI, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Andrew G WebbDepartment of Radiology, C.J. Gorter Center for High-field MRI, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Gregorius P M LuytenDepartment of Ophthalmology, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the tumour dimensions in uveal melanoma patients using 7-T ocular MRI and compare these values with conventional ultrasound imaging to provide improved information for treatment options. MATERIALS AND

methodsTen uveal melanoma patients were examined on a 7-T MRI system using a custom-built eye coil and dedicated 3D scan sequences to minimise eye-motion-induced image artefacts. The maximum tumour prominence was estimated from the three-dimensional images and compared with the standard clinical evaluation from 2D ultrasound images.

resultsThe MRI protocols resulted in high-resolution motion-free images of the eye in which the tumour and surrounding tissues could clearly be discriminated. For eight of the ten patients the MR images showed a slightly different value of tumour prominence (average 1.0 mm difference) compared to the ultrasound measurements, which can be attributed to the oblique cuts through the tumour made by the ultrasound. For two of these patients the more accurate results from the MR images changed the treatment plan, with the smaller tumour dimensions making them eligible for eye-preserving therapy.

conclusionHigh-field ocular MRI can yield a more accurate measurement of the tumour dimensions than conventional ultrasound, which can result in significant changes in the prescribed treatment.

Indexed as

UltrasonographyArtifactsBrachytherapyHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMelanomaOphthalmologyRadiotherapy Planning, Computer-AssistedUveal MelanomaUveal NeoplasmsEyeMagnetic resonance imaging (MRI)OphthalmologyUltrasoundUveal melanoma

Identifiers

PMID26915081
PMCPMC4891368
OpenAlexW2279431753

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.