Evidence map›Paper›PMID 26914937›Full record

ArticlePediatric radiology2016

Image-guided percutaneous core needle biopsy of soft-tissue masses in the pediatric population.

Terrence Metz, Amer Heider, Ranjith Vellody, Marcus D Jarboe, Joseph J Gemmete, Jason J Grove, Ethan A Smith, Rajen Mody, Erika A Newman, Jonathan R Dillman

Abstract read
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Article in Pediatric radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 41 citations in OpenAlex.

  1. Conclusiveness of biopsy techniques for diagnosis of bone and soft tissue tumours: a retrospective, single-centre observational study.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026
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  10. Quantitative imaging in medicine and surgery · 2023
    Article
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  16. Value of CT-guided percutaneous needle biopsy of bone in the diagnosis of lymphomas based on PET/CT results.Cancer imaging : the official publication of the International Cancer Imaging Society · 2019
    Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Terrence MetzDepartment of Radiology, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, MI, USA.
Amer HeiderDepartment of Pathology, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, MI, USA.
Ranjith VellodyDepartment of Radiology, Children's National Medical Center, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Marcus D JarboeSection of Pediatric Surgery, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, MI, USA.
Joseph J GemmeteDepartment of Radiology, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, MI, USA.
Jason J GroveDepartment of Radiology, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, MI, USA.
Ethan A SmithDepartment of Radiology, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, MI, USA.
Rajen ModyDepartment of Pediatrics, Division of Pediatric Hematology/Oncology, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, MI, USA.
Erika A NewmanSection of Pediatric Surgery, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, MI, USA.
Jonathan R DillmanDepartment of Radiology,Cincinnati Children's Hospital Medical Center,, University of Cincinnati College of Medicine, 3333 Burnet Ave., ML 5031, Cincinnati, OH, 45229-3039, USA. jonathan.dillman@cchmc.org.
Michigan Medicine · USCincinnati Children's Hospital Medical Center · USC. S. Mott Children's Hospital · USGeorge Washington University · USWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA paucity of literature describes the use of imaged-guided percutaneous core needle biopsy for the diagnosis and characterization of pediatric soft-tissue masses and lesions.

objectiveTo retrospectively determine whether image-guided percutaneous core needle biopsy is adequate for diagnosing and characterizing benign and malignant pediatric soft-tissue masses and lesions. MATERIALS AND

methodsWe identified children (≤18 years old) who underwent US- or CT-guided percutaneous core needle biopsy of a soft-tissue mass or other lesion between January 2012 and March 2014. Using medical records, we documented the following data: age and gender, site of the mass or lesion, size and number of biopsy specimens, whether the biopsy procedure was diagnostic, whether sufficient tissue was obtained for necessary ancillary testing (e.g., cytogenetic evaluation), and whether there was a procedural complication within 1 week.

resultsOne hundred eight soft-tissue masses or lesions were biopsied under imaging guidance in 84 children; 39 (46%) were girls. Mean age ± standard deviation (SD) was 12.1 ± 5.1 years (range 6 months to 18 years). Of these procedures, 105/108 (97%) were diagnostic; 82/108 (76%) were US-guided; 87/108 (81%) were performed using a 17-gauge introducer needle/18-gauge biopsy instrument. The mean number ± SD of core needle biopsy specimens obtained was 8.9 ± 5.0. For newly diagnosed malignancies, adequate tissue was obtained for ancillary testing in 28/30 (93%) masses. One minor complication was documented.

conclusionImage-guided percutaneous core needle biopsy of pediatric soft-tissue masses is safe, has a high diagnostic rate, and provides sufficient tissue for ancillary testing.

Indexed as

Radiography, InterventionalTomography, X-Ray ComputedUltrasonography, InterventionalAdolescentBiopsy, Large-Core NeedleChildChild, PreschoolFemaleHumansImage-Guided BiopsyInfantMaleRetrospective StudiesSoft Tissue NeoplasmsChildrenComputed tomographyImage-guidedMassNeoplasmPercutaneous core needle biopsyUltrasound

Identifiers

PMID26914937
OpenAlexW2285747646

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.