ArticlePloS one2016
Half of Pulmonary Tuberculosis Cases Were Left Undiagnosed in Prisons of the Tigray Region of Ethiopia: Implications for Tuberculosis Control.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Pooled it
- Epidemiology of TB in prisoners: a metanalysis of the prevalence of active and latent TB.BMC infectious diseases · 2023Pooled it
- Prevalence of tuberculosis among prisoners in sub-Saharan Africa: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Number needed to screen for TB in clinical, structural or occupational risk groups.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022Pooled it
- Magnitude, associated risk factors, and trend comparisons of identified tuberculosis types among prisons in Ethiopia: A systematic review and meta-analysis.Health science reports · 2024Article
- Spiritual Holy Water Sites in Ethiopia: Unrecognized High-Risk Settings for Transmission of Pulmonary Tuberculosis.International journal of microbiology · 2024Article
- Missed opportunity for tuberculosis screening among patients presenting at two health facilities in Manafwa district, Uganda.Journal of public health in Africa · 2023Article
- Active Screening for Pulmonary Tuberculosis Among Jail Inmates: A Mixed Method Study From Puducherry, South India.Cureus · 2023Article
- Article
- Prevalence and Predictors of Pulmonary Tuberculosis among Prison Inmates in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.Tuberculosis research and treatment · 2023Article
- Pooling Sputum Samples for Efficient Mass Tuberculosis Screening in Prisons.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Substance use disorders and adherence to antituberculosis medications in Southwest Ethiopia: a prospective cohort study.BMJ open · 2021Article
- Tuberculosis active case-finding interventions and approaches for prisoners in sub-Saharan Africa: a systematic scoping review.BMC infectious diseases · 2020Article
- Magnitude and predictors of khat use among patients with tuberculosis in Southwest Ethiopia: A longitudinal study.PloS one · 2020Article
- Tuberculosis Case Finding Cascade and Treatment Outcomes among Male Inmates in Two Prisons in Zimbabwe.Tuberculosis research and treatment · 2020Article
- Epidemic Situation of Tuberculosis in Prisons in the Central Region of China.The American journal of tropical medicine and hygiene · 2019Article
- High utility of active tuberculosis case finding in an Ethiopian prison.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2018Article
- Tuberculosis treatment outcome and predictors in northern Ethiopian prisons: a five-year retrospective analysis.BMC pulmonary medicine · 2018Article
- Emerging epidemic of drug resistant tuberculosis in vulnerable populations of developing countries.African health sciences · 2017Article
- One-fourth of the prisoners are underweight in Northern Ethiopia: a cross-sectional study.BMC public health · 2017Article
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Authors and funding
6 authors.
Funding
Abstract
introductionPrison settings have been often identified as important but neglected reservoirs for TB. This study was designed to determine the prevalence of undiagnosed pulmonary TB and assess the potential risk factors for such TB cases in prisons of the Tigray region.
methodA cross-sectional study was conducted between August 2013 and February 2014 in nine prisons. A standardized symptom-based questionnaire was initially used to identify presumptive TB cases. From each, three consecutive sputum samples were collected for acid-fast bacilli (AFB) microscopy and culture. Blood samples were collected from consented participants for HIV testing.
resultOut of 809 presumptive TB cases with culture result, 4.0% (95% CI: 2.65-5.35) were confirmed to have undiagnosed TB. The overall estimated point prevalence of undiagnosed TB was found to be 505/100,000 prisoners (95% CI: 360-640). Together with the 27 patients who were already on treatment, the overall estimated point prevalence of TB would be 793/100,000 prisoners (95% CI: 610-970), about four times higher than in the general population. The ratio of active to passive case detection was 1.18:1. The prevalence of HIV was 4.4% (36/809) among presumptive TB cases and 6.3% (2/32) among undiagnosed TB cases. In a multivariate logistic regression analysis, chewing Khat (adjusted OR = 2.81; 95% CI: 1.02-7.75) and having had a close contact with a TB patient (adjusted OR = 2.18; 95% CI: 1.05-4.51) were found to be predictors of undiagnosed TB among presumptive TB cases.
conclusionsThis study revealed that at least half of symptomatic pulmonary TB cases in Northern Ethiopian prisons remain undiagnosed and hence untreated. The prevalence of undiagnosed TB in the study prisons was more than two folds higher than in the general population of Tigray. This may indicate the need for more investment and commitment to improving TB case detection in the study prisons.
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