Evidence map›Paper›PMID 26914696›Full record

ArticleEuropean radiology2016

18F-FDG PET/CT assessment of histopathologically confirmed mediastinal lymph nodes in non-small cell lung cancer using a penalised likelihood reconstruction.

Eugene J Teoh, Daniel R McGowan, Kevin M Bradley, Elizabeth Belcher, Edward Black, Alastair Moore, Annemarie Sykes, Fergus V Gleeson

Open access · hybridAbstract readEvaluation Study
In one paragraph

Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 56 citations in OpenAlex.

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  8. Image enhancement of whole-body oncology [European journal of nuclear medicine and molecular imaging · 2022
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  9. Changes of [BMC medical imaging · 2021
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  10. New PET technologies - embracing progress and pushing the limits.European journal of nuclear medicine and molecular imaging · 2021
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  11. Article
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  18. Bayesian penalised likelihood reconstruction (Q.Clear) ofThe British journal of radiology · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Eugene J TeohDepartment of Radiology, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 7LE, UK.
Daniel R McGowanDepartment of Oncology, University of Oxford, Oxford, OX3 7DQ, UK. daniel.mcgowan@oncology.ox.ac.uk.
Kevin M BradleyDepartment of Radiology, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 7LE, UK.
Elizabeth BelcherDepartment of Thoracic Surgery, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 9DU, UK.
Edward BlackDepartment of Thoracic Surgery, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 9DU, UK.
Alastair MooreDepartment of Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 7LE, UK.
Annemarie SykesDepartment of Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 7LE, UK.
Fergus V GleesonDepartment of Radiology, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 7LE, UK.
University of Oxford · GBChurchill Hospital · GBJohn Radcliffe Hospital · GB

Funding

Cancer Research UK 16466Department of Health NIHR-HCS-D12-03-13
6 · The paper itself

Abstract

purposeTo investigate whether using a Bayesian penalised likelihood reconstruction (BPL) improves signal-to-background (SBR), signal-to-noise (SNR) and SUV MATERIALS AND

methods18F-FDG PET/CT scans for NSCLC staging in 47 patients (112 nodal stations with histopathological confirmation) were reconstructed using BPL and compared to OSEM. Node and multiple background SUV parameters were analysed semi-quantitatively and visually.

resultsComparing BPL to OSEM, there were significant increases in SUV

conclusionBPL increases SBR, SNR and SUV KEY POINTS: • Penalised likelihood PET reconstruction was applied for assessing mediastinal nodes in NSCLC. • The new reconstruction generated significant increases in signal-to-background, signal-to-noise and SUVmax. • This led to an improvement in visual sensitivity using the new algorithm. • Higher SUV

Indexed as

Fluorodeoxyglucose F18RadiopharmaceuticalsAdultAgedAged, 80 and overAlgorithmsCarcinoma, Non-Small-Cell LungEpidemiologic MethodsFemaleHumansLung NeoplasmsLymphatic MetastasisLymph NodesMaleMiddle AgedMultimodal ImagingFluorodeoxyglucose F18RadiopharmaceuticalsBayesianLung cancer stagingMediastinal nodesPET-CTPET reconstructionSignal-to-noise

Identifiers

PMID26914696
PMCPMC4898597
OpenAlexW2275859908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.