Trial reportLasers in medical science2016
Efficacy of high-intensity laser therapy in the treatment of chronic neck pain: a randomized double-blind placebo-control trial.
Trial report in Lasers in medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of High Intensity Laser Therapy (HILT) and Stretching Exercises on Cervical Flexibility and Pain Reduction in Myofascial Trigger Points. Randomized Clinical Trial (RCT).
Clinical Effectiveness of High-Intensity Laser Therapy in Patients With Cervical Radiculopathy: A Randomized Study of Double Blınd With Sham Control
Effect of High-intensity Laser Therapy in Patients With Chronic Nonspecific Neck Pain. Randomized Clinical Trial
Effect of High Power Laser Therapy on Pain and Electrophysiological Study in Cervical Radiculopathy Patients: Randomized Controlled Trial
The Effect of High-power Laser Therapy on Pain, Functional Disability, Range of Motion and Pressure Pain Threshold in Subjects With Radicular Low Back Pain Due to Intervertebral Disc Herniation: A Double-blind Randomised Controlled Trial
Effectiveness of High Intensity Laser Treatment in Partial Supraspinatus Tendon Tears: A Randomised Controlled Trial
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Efficacy of high-intensity laser therapy for patellofemoral pain: a systematic review and meta-analysis.Chiropractic & manual therapies · 2026Pooled it
- Comparative effectiveness of six biophysical agents on neck pain rehabilitation: a systematic review and network meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Pooled it
- A systematic review and meta-analysis of randomized controlled trials on the effectiveness of high-intensity laser therapy in the management of neck pain.Lasers in medical science · 2024Pooled it
- Pooled it
- Effect of class IV LASER therapy along with Low-dye kinesio-taping technique or plantar fascia stretching on pain, pain pressure threshold, and disability in individuals with plantar fasciitis: Double-blinded randomized clinical trial.Lasers in medical science · 2026Trial
- Effectiveness of high intensity laser treatment in partial supraspinatus tendon tears: a randomised controlled trial.Lasers in medical science · 2025Trial
- Effect of high-intensity laser therapy versus shockwave therapy on selected outcome measures in osteoporotic long-term hemiparetic patients: a randomized control trial.Journal of orthopaedic surgery and research · 2023Trial
- Effectiveness of High Power Laser Therapy on Pain and Isokinetic Peak Torque in Athletes with Proximal Hamstring Tendinopathy: A Randomized Trial.BioMed research international · 2022Trial
- The effect of high intensity laser therapy in the management of painful calcaneal spur: a double blind, placebo-controlled study.Lasers in medical science · 2020Trial
- Efficacy of pulsed Nd:YAG laser in the treatment of patients with knee osteoarthritis: a randomized controlled trial.Lasers in medical science · 2017Trial
- Short-term effects of high-intensity laser therapy, manual therapy, and Kinesio taping in patients with subacromial impingement syndrome.Lasers in medical science · 2016Trial
- The 28-year evolution of laser acupuncture: a CiteSpace knowledge graph visualization and analysis.Lasers in medical science · 2025Review
- Efficacy of a wearable 660 nm red light therapy device in alleviating neck pain and enhancing neck function.Lasers in medical science · 2025Article
- Pulsed Nd:YAG laser therapy accelerates fracture healing in a rat femoral osteotomy model.Bone & joint research · 2025Article
- Immediate effects of high-intensity laser therapy for nonspecific neck pain: a double-blind randomized controlled trial.Frontiers in medicine · 2025Article
- Photobiomodulation on shoulder and neck pain and disability: A comprehensive review.Lasers in medical science · 2024Review
- The Effectiveness of High Intensity Laser in Improving Motor Deficits in Patients with Lumbar Disc Herniation.Life (Basel, Switzerland) · 2024Article
- High-Intensity Laser Therapy in Pain Management of Knee Osteoarthritis.Biomedicines · 2024Review
- The Pulsed Nd:YAG Laser Therapy Enhanced Nerve Regeneration via Apoptosis Inhibition in a Rat Crushed Sciatic Nerve Model.Neurochemical research · 2024Article
- High-frequency laser therapy: a new alternative to physiotherapy in the treatment of cervical disk hernia.Frontiers in medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to investigate the effect of high-intensity laser therapy (HILT) in treatment of patients with chronic neck pain (CNP) on cervical range of motion (ROM), pain, and functional activity. Sixty male patients participated in this study with mean (SD) age of 35.47 (4.18) years. Patients were randomly assigned into two groups and treated with HILT plus exercise (HILT + EX) and placebo laser plus exercise (PL + EX) in groups 1 and 2, respectively. The outcomes measured were cervical ROM, pain level by visual analog scale (VAS), and functional activity by neck disability index (NDI) score. Statistical analyses were performed to compare the differences between baseline and post-treatment. The level of statistical significance was set as p < 0.05. Cervical ROM significantly increased after 6 weeks of treatment in all groups. VAS and NDI results showed significant decrease post-treatment in both groups. HILT + EX effectively increased cervical ROM and decreased VAS and NDI scores after 6 weeks of treatment compared to PL + EX. HILT + EX is an effective physical therapy modality for patients with CNP compared to PL + EX therapy. The combination of HILT + EX effectively increased cervical ROM, functional activity, and reduced pain after 6 weeks of treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.