Evidence map›Paper›PMID 26914538›Full record

ArticleActa haematologica2016

Haploidentical Donors: Can Faster Transplantation Be Life-Saving for Patients with Advanced Disease?

Alina Tanase, Ciprian Tomuleasa, Alexandra Marculescu, Alexandru Bardas, Anca Colita, Carmen Orban, Stefan Octavian Ciurea

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In one paragraph

Article in Acta haematologica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
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  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Alina TanaseDepartment of Stem Cell Transplantation, Fundeni Clinical Institute, Bucharest, Romania.
Ciprian Tomuleasa
Alexandra Marculescu
Alexandru Bardas
Anca Colita
Carmen Orban
Stefan Octavian Ciurea

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Haploidentical stem cell transplantation is a therapeutic option for patients without an HLA-matched donor. It is increasingly being used worldwide due to the application of posttransplantation cyclophosphamide and is associated with lower incidence of graft-versus-host disease and treatment-related mortality. Haploidentical donors are generally available for most patients and stem cells can be rapidly obtained. Delays in transplantation while waiting for unrelated donor cells can be potentially problematic for patients with advanced disease at risk for progression; thus, the use of haploidentical donors, especially in this setting, can be life-saving. Here we reviewed the literature on haploidentical stem cell transplantation performed with posttransplantation cyclophosphamide.

Indexed as

Histocompatibility TestingCyclophosphamideGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansIncidenceTransplantation ConditioningTransplantation, HomologousUnrelated DonorsCyclophosphamide

Identifiers

PMID26914538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.