SynthesisPloS one2016
Electroencephalographic Patterns in Chronic Pain: A Systematic Review of the Literature.
Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 123 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Feasibility of a Brain-Computer Interface (BCI)-Based Adaptive Sensing and Feedback for Chronic Pain Management
Contemporary Pain Neuroscience Compared to Usual Care Evidence-based Physiotherapy Applied to Chronic Pain in Patients With Chronic Whiplash Associated Disorders: Can we Decrease Central Sensitization?
Evidence for Central Sensitization in Patients With Chronic Whiplash Associated Disorders Based on Self-reported Outcomes of Pain (Beliefs), Disability, Central Sensitization, Quantitative Sensory Testing, and Electro-encephalography.
Who cites it
123 citing papers in PubMed, 6 syntheses or guidelines pooled it, 258 citations in OpenAlex.
- Potential applications of artificial intelligence in pain management: a scoping review.Frontiers in pain research (Lausanne, Switzerland) · 2026Pooled it
- State of the art in EEG signal features of mindfulness-based treatments for chronic pain.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- The efficacy and mechanisms of low-intensity transcranial ultrasound stimulation on pain: a systematic review of human and animal studies.The journal of headache and pain · 2025Pooled it
- Does brain entrainment using binaural auditory beats affect pain perception in acute and chronic pain?: a systematic review.BMC complementary medicine and therapies · 2024Pooled it
- Neurofeedback for Pain Management: A Systematic Review.Frontiers in neuroscience · 2020Pooled it
- The association between visual impairment and fatigue: a systematic review and meta-analysis of observational studies.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2019Pooled it
- Audio-visual stimulation therapy for chronic neuropathic pain: a sham-controlled randomized clinical trial.BMC neurology · 2026Trial
- Positive Emotion Dysregulation in Opioid Use Disorder and Normalization by Mindfulness-Oriented Recovery Enhancement: A Secondary Analysis of a Randomized Clinical Trial.JAMA psychiatry · 2025Trial
- Brain compensatory mechanisms in depression and memory complaints in fibromyalgia: the role of theta oscillatory activity.Pain medicine (Malden, Mass.) · 2024Trial
- Effect of multidimensional physiotherapy on non-specific chronic low back pain: a randomized controlled trial.Advances in rheumatology (London, England) · 2023Trial
- An Educational and Exercise Mobile Phone-Based Intervention to Elicit Electrophysiological Changes and to Improve Psychological Functioning in Adults With Nonspecific Chronic Low Back Pain (BackFit App): Nonrandomized Clinical Trial.JMIR mHealth and uHealth · 2022Trial
- Comparison of two tDCS protocols on pain and EEG alpha-2 oscillations in women with fibromyalgia.Scientific reports · 2020Trial
- Decreased neural inhibitory state in fibromyalgia pain: A cross-sectional study.Neurophysiologie clinique = Clinical neurophysiology · 2020Trial
- Individual variation in alpha neurofeedback training efficacy predicts pain modulation.NeuroImage. Clinical · 2020Trial
- Identifying and Engaging Neuronal Oscillations by Transcranial Alternating Current Stimulation in Patients With Chronic Low Back Pain: A Randomized, Crossover, Double-Blind, Sham-Controlled Pilot Study.The journal of pain · 2019Trial
- Electroencephalography research in neuropathic pain (Review).Molecular medicine reports · 2026Review
- EEG-based clustering shows distinct separation of chronic pain patients before spinal cord stimulation surgery.NeuroImage · 2026Article
- The role of catastrophizing in anxiety and depression symptom scores among knee osteoarthritis patients: a multimodal assessment with EEG and machine learning.Experimental brain research · 2026Article
- Chiropractic Care Is Associated with Frequency-Specific Reorganisation of Triple-Network Brain Dynamics: A Source-Localised EEG Study.Brain sciences · 2026Article
- EEG neurofeedback for the treatment of neuropathic pain in the elderly-a mechanistic review.GeroScience · 2026Review
63 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The main objective of this study is to review and summarize recent findings on electroencephalographic patterns in individuals with chronic pain. We also discuss recent advances in the use of quantitative Electroencephalography (qEEG) for the assessment of pathophysiology and biopsychosocial factors involved in its maintenance over time. Data collection took place from February 2014 to July 2015 in PubMed, SciELO and PEDro databases. Data from cross-sectional studies and longitudinal studies, as well as clinical trials involving chronic pain participants were incorporated into the final analysis. Our primary findings related to chronic pain were an increase of theta and alpha EEG power at rest, and a decrease in the amplitude of evoked potentials after sensory stimulation and cognitive tasks. This review suggests that qEEG could be considered as a simple and objective tool for the study of brain mechanisms involved in chronic pain, as well as for identifying the specific characteristics of chronic pain condition. In addition, results show that qEEG probably is a relevant outcome measure for assessing changes in therapeutic studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.