Evidence map›Paper›PMID 26914096›Full record

SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2016

The location of Modic changes in the lumbar spine: a meta-analysis.

Zhe-Yu Huang, Hai-Chao Xu, Tao Lei, Qing-Long Li, Ai-Min Wu, Wen-Fei Ni

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Spinal disorders mimicking infection.Insights into imaging · 2021
    Review
  5. Article
  6. New insights into the natural course and clinical relevance of Modic changes over 2 years following lumbar limited discectomy: analysis of prospective collected data.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019
    Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhe-Yu HuangThe Department of Orthopedics Surgery, Second Affiliated Hospital of Wenzhou Medical University, 109# XueYuan Western Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Hai-Chao XuThe Department of Orthopedics Surgery, Second Affiliated Hospital of Wenzhou Medical University, 109# XueYuan Western Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Tao LeiThe Department of Orthopedics Surgery, Second Affiliated Hospital of Wenzhou Medical University, 109# XueYuan Western Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Qing-Long LiThe Department of Orthopedics Surgery, Second Affiliated Hospital of Wenzhou Medical University, 109# XueYuan Western Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Ai-Min WuThe Department of Orthopedics Surgery, Second Affiliated Hospital of Wenzhou Medical University, 109# XueYuan Western Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Wen-Fei NiThe Department of Orthopedics Surgery, Second Affiliated Hospital of Wenzhou Medical University, 109# XueYuan Western Road, Wenzhou, 325027, Zhejiang, People's Republic of China. wenfeini@yeah.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis meta-analysis was to study the location of Modic changes in the lumbar spine.

methodsThe electronic databases including MEDLINE, Web of science, Cochrane Central Register of Controlled Trials, OVID, CBM were searched. Relevant studies that described the patients with Modic Changes were included. Data were extracted and analysed using the version 12.0 STATA software.

resultsThirty-one studies were selected and analyzed (2346 total patients). No significant differences of the incidence of MC were identified between superior and the inferior end plates adjacent to discs [RR = 1.04, 95 % CI (0.74, 1.53)], the same result was detected for the distribution of MC type I between L4/5 and L5/S1 [RR = 0.80, 95 % CI (0.64, 1.02)]. While lower lumbar spine (L4/5, L5/S1) had significant greater incidence of MC [RR = 0.20, 95 % CI (0.15, 0.25)], especially in L5/S1 [RR = 0.82, 95 % CI (0.72, 0.92)]. For MC type II, it also significantly appeared in L5/S1 [RR = 0.80, 95 % CI (0.67, 0.95), P = 0.010].

conclusionsIn this study, Modic Changes was more common in the lowest two levels, especially in L5/S1. Additionally, the sub-types (type I and type II) were also more likely to appear in L5/S1. It appeared that there existed a correlation between MC and biomechanics. And it seemed that local biomechanical stress might contributed to the distribution of MC and the conversion of type I to type II for the patients treated conservatively.

Indexed as

Magnetic Resonance ImagingHumansIntervertebral DiscIntervertebral Disc DegenerationLumbar VertebraeDegenerationLocationLumbar spineModic change(s)Vertebral endplate(s)

Identifiers

PMID26914096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.