Evidence map›Paper›PMID 26913786›Full record

Trial reportThe journal of spinal cord medicine2016

Changes in pain and quality of life in depressed individuals with spinal cord injury: does type of pain matter?

Elizabeth J Richardson, Larry G Brooks, J Scott Richards, Charles H Bombardier, Jason Barber, Denise Tate, Martin B Forchheimer, Jesse R Fann

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The journal of spinal cord medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elizabeth J Richardsona Department of Physical Medicine and Rehabilitation , University of Alabama at Birmingham , Birmingham , AL , USA.
Larry G Brooksb Department of Rehabilitation Medicine , University of Miami , Miami , Florida , USA.
J Scott Richardsc Department of Physical Medicine and Rehabilitation , University of Alabama at Birmingham , Birmingham , AL , USA.
Charles H Bombardierd Department of Rehabilitation Medicine , University of Washington , Seattle , WA , USA.
Jason Barbere Department of Psychiatry and Behavioral Sciences , University of Washington , Seattle , WA , USA.
Denise Tatef Department of Physical Medicine and Rehabilitation , University of Michigan , Ann Arbor , MI , USA.
Martin B Forchheimerf Department of Physical Medicine and Rehabilitation , University of Michigan , Ann Arbor , MI , USA.
Jesse R Fanne Department of Psychiatry and Behavioral Sciences , University of Washington , Seattle , WA , USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the association of neuropathic and nociceptive pain severity and interference with quality of life (QoL) in persons with spinal cord injury (SCI) who underwent a randomized controlled 12-week trial of an antidepressant to treat depression. A secondary objective was to assess the effect of changes in pain on mobility and physical independence.

designMultivariable ANCOVA models controlling for relevant demographic covariates, treatment condition, and baseline pain and QoL were used.

settingSix rehabilitation centers.

participantsOf the 133 persons who were randomized into the trial, 108 provided pain severity and interference ratings through follow-up.

interventionsNot applicable. OUTCOME MEASURES: The Satisfaction with Life Scale and the physical and mental component summary scores of the 12-Item Short-Form Health Survey (SF-12). Secondary outcome measures included the mobility and physical independence subscales of the Craig Handicap Assessment and Reporting Technique (CHART).

resultsBroadly, few associations between pain and QoL were evident. Results revealed relationships between lower baseline nociceptive pain interference and higher satisfaction with life and mental health-related QoL at 12 weeks. Similarly, lower neuropathic pain interference was associated with change in physical independence, but unrelated to mobility.

conclusionsPain interference over time may be differentially related to QoL outcomes based on the type of pain following SCI, but overall, there were no extensive relationships between pain and QoL in this sample of depressed persons with SCI.

Indexed as

Quality of LifeActivities of Daily LivingAdolescentAdultAntidepressive AgentsDepressionFemaleHumansMaleMiddle AgedNeuralgiaNociceptive PainSpinal Cord InjuriesAntidepressive AgentsNeuropathic painPainQuality of lifeSpinal cord injury

Identifiers

PMID26913786
PMCPMC5020591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.