ArticleInternational journal of spine surgery2016
Vertebroplasty and kyphoplasty for cervical spine metastases: a systematic review and meta-analysis.
Article in International journal of spine surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- When Less Is More: The indications for MIS Techniques and Separation Surgery in Metastatic Spine Disease.Spine · 2016Pooled it
- Anterior mini-incision vesselplasty using bone filling container for C2 metastasis: a single center case series.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- What is the Optimal Management of Metastatic Spine Patients With Intermediate Spinal Instability Neoplastic Scores: To Operate or Not to Operate?Global spine journal · 2025Article
- Joint International SILACO, SICCMII, ISASS Symposium as a Model for a Collaborative Framework to Create Literature on Advances in Spine Surgery, Patient Care, and Policy.International journal of spine surgery · 2022Article
- Results of percutaneous cervical vertebroplasty using an anterolateral approach for cervical spine tumors.Acta orthopaedica et traumatologica turcica · 2022Article
- Vessel-Plasty Using Bone-Filling Mesh Container for Treatment of Malignant Severe Compression Fractures in Cervical Vertebrae.Journal of pain research · 2022Article
- Basivertebral foramina of true vertebrae: morphometry, topography and clinical considerations.Surgical and radiologic anatomy : SRA · 2021Article
- Percutaneous vertebroplasty of the cervical spine performed via a posterior trans-pedicular approach.European radiology · 2021Article
- Combined Percutaneous Kyphoplasty/Pediculoplasty by Posterolateral Transpedicular Approach for Painful Cervical Spine Metastases: A Single-Center Prospective Study.Journal of pain research · 2021Article
- Safety and effectiveness of cervical vertebroplasty: report of a large cohort and systematic review.European radiology · 2020Article
- Complications of spine surgery for metastasis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2020Review
- An Experimental Intervention Study Assessing the Impact of a Thin Silicone Gel Surface Overlay on Interface Pressure.Radiology research and practice · 2020Article
- Balloon kyphoplasty and additional anterior odontoid screw fixation for treatment of unstable osteolytic lesions of the vertebral body C2: a case series.BMC musculoskeletal disorders · 2018Article
- Surgical treatment for metastases of the cervical spine.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2017Article
- Minimally Invasive Surgical Techniques for Management of Painful Metastatic and Primary Spinal Tumors.Cureus · 2017Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVertebroplasty (VP) and kyphoplasty (KP) are two minimally invasive techniques used to relieve pain and restore stability in metastatic spinal disease. However, most of these procedures are performed in the thoracolumbar spine, and there is limited data on outcomes after VP/KP for cervical metastases. The purpose of this article is to evaluate the safety and efficacy of VP and KP for treating pain in patients with cervical spine metastases.
methodsA systematic review of the literature was conducted using the PubMed and Medline databases. Only studies that reported five or more patients treated with VP/KP in the cervical spine were included. Levels of evidence and grades of recommendation were established based on the Oxford Centre for Evidence-Based Medicine guidelines. Data was pooled to perform a meta-analysis for pain relief and complication rates.
resultsSix studies (all level 4 studies) met the inclusion criteria, representing 120 patients undergoing VP/KP at 135 vertebrae; the most common addressed level was C2 in 83 cases. The average volume of injected cement was 2.5 ± 0.5 milliliters at each vertebra. There were 22 asymptomatic cement leaks (16%; 95% CI, 9.8% - 22.2%) most commonly occurring in the paraspinal soft tissue. There were 5 complications (4%; 95% CI, 0.5% - 7.5%): 3 cases of mild odynophagia, 1 case of occipital neuralgia secondary to leak, and 1 case of stroke secondary to cement embolism. Pain relief was achieved in 89% of cases (range: 80 - 100%). The calculated average pain score decreased significantly from 7.6 ± 0.9 before surgery to 1.9 ± 0.8 at last evaluation (p=0.006).
conclusionAlthough the calculated complication rate after VP/KP in the cervical spine is low (4%) and the reported pain relief rate is approximately 89%, there is lack of high-quality evidence supporting this. Future randomized controlled trials are needed.
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