ArticleEnvironmental epigenetics2015
PON1 as a model for integration of genetic, epigenetic, and expression data on candidate susceptibility genes.
Article in Environmental epigenetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- The interaction between a leflunomide-response methylation site (cg17330251) and variant (rs705379) on response to leflunomide in patients with rheumatoid arthritis.Frontiers in pharmacology · 2025Article
- Comparison of DNA methylation measurements from EPIC BeadChip and SeqCap targeted bisulphite sequencing in PON1 and nine additional candidate genes.Epigenetics · 2022Article
- The Relationship between Cancer and Paraoxonase 1.Antioxidants (Basel, Switzerland) · 2022Review
- Insights into the role of paraoxonase 2 in human pathophysiology.Journal of biosciences · 2022Article
- Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR.Epigenetics & chromatin · 2021Article
- A targeted multi-omics approach reveals paraoxonase-1 as a determinant of obesity-associated fatty liver disease.Clinical epigenetics · 2021Article
- Association of laboratory parameters and genetic polymorphisms with ischemic stroke in Chinese Han population.Experimental and therapeutic medicine · 2021Article
- AHR gene-dioxin interactions and birthweight in the Seveso Second Generation Health Study.International journal of epidemiology · 2018Article
- PON1 DNA methylation and neurobehavior in Mexican-American children with prenatal organophosphate exposure.Environment international · 2018Article
- Associations of miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms with Ischemic Stroke in the Northern Chinese Han Population.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Organophosphate neurotoxicity to the voluntary motor system on the trail of environment-caused amyotrophic lateral sclerosis: the known, the misknown, and the unknown.Archives of toxicology · 2017Review
- Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group.Environmental health perspectives · 2017Article
- Persistent DNA methylation changes associated with prenatal mercury exposure and cognitive performance during childhood.Scientific reports · 2017Article
- Future of environmental research in the age of epigenomics and exposomics.Reviews on environmental health · 2017Review
- Linking the Epigenome with Exposure Effects and Susceptibility: The Epigenetic Seed and Soil Model.Toxicological sciences : an official journal of the Society of Toxicology · 2017Review
- CpG Methylation across the adipogenic PPARγ gene and its relationship with birthweight and child BMI at 9 years.BMC medical genetics · 2017Article
- Interaction between prenatal pesticide exposure and a common polymorphism in theClinical epigenetics · 2017Article
- Article
- Q192R polymorphism in the PON1 gene and familial hypercholesterolemia in a Saudi population.Annals of Saudi medicineArticle
- Influence of nutritional factors and the PON1 C(-107)T polymorphism on paraoxonase-1 activity in childhood.Jornal de pediatriaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Recent genome- and epigenome-wide studies demonstrate that the DNA methylation is controlled in part by genetics, highlighting the importance of integrating genetic and epigenetic data. To better understand molecular mechanisms affecting gene expression, we used the candidate susceptibility gene paraoxonase 1 (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.