A fatty acid in the MCT ketogenic diet for epilepsy treatment blocks AMPA receptors.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

1. Therapeutic Efficacy of Intermittent Ketogenesis in Modulating Adenosine Metabolism, Immune Response, and Seizure Severity in Refractory Temporal Lobe Epilepsy: A Pilot Human Study.Inflammation · 2025
   Article
2. Ketogenic Metabolism in Neurodegenerative Diseases: Mechanisms of Action and Therapeutic Potential.Metabolites · 2025
   Review
3. Oral glutamine supplementation increases seizure severity in a rodent model of mesial temporal lobe epilepsy.Nutritional neuroscience · 2022
   Article
4. Nutritional ketosis as an intervention to relieve astrogliosis: Possible therapeutic applications in the treatment of neurodegenerative and neuroprogressive disorders.European psychiatry : the journal of the Association of European Psychiatrists · 2020
   Review
5. Metabolic Control of Epilepsy: A Promising Therapeutic Target for Epilepsy.Frontiers in neurology · 2020
   Review
6. Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives.Frontiers in neuroscience · 2019
   Review
7. Design and Comparative Evaluation of the Anticonvulsant Profile, Carbonic-Anhydrate Inhibition and Teratogenicity of Novel Carbamate Derivatives of Branched Aliphatic Carboxylic Acids with 4-Aminobenzensulfonamide.Neurochemical research · 2017
   Article
8. The Current Status of the Ketogenic Diet in Psychiatry.Frontiers in psychiatry · 2017
   Review

Corrections and comments

• Comment on
  Seizure control by decanoic acid through direct AMPA receptor inhibition.2016

Authors and funding

1 author at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as