ArticlePlant physiology2016
HvPap-1 C1A Protease and HvCPI-2 Cystatin Contribute to Barley Grain Filling and Germination.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Activity-Based Profiling of Papain-like Cysteine Proteases in Different Plant Organs During Barley Development.Plants (Basel, Switzerland) · 2026Article
- Regulation of Pollen Viability, Pollen Tube Growth and Seed Development in Maize by Application of Cysteine Protease ZmPCP.Plants (Basel, Switzerland) · 2026Article
- Salinity inhibits seed germination and embryo growth by reducing starch mobilization efficiency in barley.Plant direct · 2024Article
- Characterization and Differentiation of Grain Proteomes from Wild-Type Puroindoline and Variants in Wheat.Plants (Basel, Switzerland) · 2023Article
- How Cysteine Protease GeneInternational journal of molecular sciences · 2021Article
- Article
- Genome-Wide Identification and Expression Analysis of the Protease Inhibitor Gene Families in Tomato.Genes · 2019Article
- Insights on the Proteases Involved in Barley and Wheat Grain Germination.International journal of molecular sciences · 2019Review
- Plant Proteases: From Key Enzymes in Germination to Allies for Fighting Human Gluten-Related Disorders.Frontiers in plant science · 2019Article
- Modulation of autophagy and protease activities by small bioactive compounds to reduce cell death and improve stress-induced microspore embryogenesis initiation in rapeseed and barley.Plant signaling & behavior · 2019Article
- Differential response of silencing HvIcy2 barley plants against Magnaporthe oryzae infection and light deprivation.BMC plant biology · 2018Article
- Autophagy is activated and involved in cell death with participation of cathepsins during stress-induced microspore embryogenesis in barley.Journal of experimental botany · 2018Article
- Role of Papain-Like Cysteine Proteases in Plant Development.Frontiers in plant science · 2018Review
- HvPap-1 C1A Protease Participates Differentially in the Barley Response to a Pathogen and an Herbivore.Frontiers in plant science · 2017Article
- Phytocystatins: Defense Proteins against Phytophagous Insects and Acari.International journal of molecular sciences · 2016Review
Corrections and comments
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Authors and funding
11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Proteolysis is an essential process throughout the mobilization of storage proteins in barley (Hordeum vulgare) grains during germination. It involves numerous types of enzymes, with C1A Cys proteases the most abundant key players. Manipulation of the proteolytic machinery is a potential way to enhance grain yield and quality, and it could influence the mobilization of storage compounds along germination. Transgenic barley plants silencing or over-expressing the cathepsin F-like HvPap-1 Cys protease show differential accumulation of storage molecules such as starch, proteins, and free amino acids in the grain. It is particularly striking that the HvPap-1 artificial microRNA lines phenotype show a drastic delay in the grain germination process. Alterations to the proteolytic activities in the over-expressing and knock-down grains associated with changes in the level of expression of several C1A peptidases were also detected. Similarly, down-regulating cystatin Icy-2, one of the proteinaceous inhibitors of the cathepsin F-like protease, also has important effects on grain filling. However, the ultimate physiological influence of manipulating a peptidase or an inhibitor cannot be always predicted, since the plant tries to compensate the modified proteolytic effects by modulating the expression of some other peptidases or their inhibitors.
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