Evidence map›Paper›PMID 26911910›Full record

ArticleNature cell biology2016

Chromosomes at loose ends.

Yuko Nakajima, James E Haber

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Yuko NakajimaDepartment of Biology and Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts, USA.
James E HaberDepartment of Biology and Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts, USA.

Funding

Recombination Mechanisms in Yeast Cell DifferentiationR37GM020056 · NIGMS · BRANDEIS UNIVERSITY · PI HABER, JAMES E · 2007 to 2016
$5.5M
Analysis of Break-Induced ReplicationR01GM076020 · NIGMS · BRANDEIS UNIVERSITY · PI HABER, JAMES E · 2006 to 2017
$3.4M
The Mechanism of Spindle Assembly Checkpoint Control in DNA Damage ResponseF32GM106524 · NIGMS · BRANDEIS UNIVERSITY · PI NAKAJIMA, YUKO · 2013 to 2017
$180k
NIGMS NIH HHS F32 GM106524NIGMS NIH HHS R01 GM076020NIGMS NIH HHS R37 GM020056
6 · The paper itself

Abstract

Broken ends of a budding yeast chromosome exhibit increased mobility, presumably to facilitate repair by recombination. A new study reports that increased mobility reflects the untethering of the broken chromosome, triggered by a DNA damage response that phosphorylates the Cep3 kinetochore protein and weakens the association between the centromere and the spindle pole body.

Indexed as

CentromereChromatinDNA-Binding ProteinsDNA RepairKinetochoresNuclear ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsChromatinDNA-Binding ProteinsNuclear ProteinsSaccharomyces cerevisiae Proteins

Identifiers

PMID26911910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.