Evidence map›Paper›PMID 26911579›Full record

ArticleEnvironmental health : a global access science source2016

Air pollution exposure and gestational diabetes mellitus among pregnant women in Massachusetts: a cohort study.

Abby F Fleisch, Itai Kloog, Heike Luttmann-Gibson, Diane R Gold, Emily Oken, Joel D Schwartz

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 99 citations in OpenAlex.

  1. Pooled it
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  10. Association Between Individual Air Pollution (PMJournal of Korean medical science · 2024
    Observational
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  19. PMAtmospheric environment (Oxford, England : 1994) · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Abby F FleischDivision of Endocrinology, Boston Children's Hospital, 300 Longwood Ave., Boston, MA, 02115, USA. abby.fleisch@childrens.harvard.edu.
Itai KloogDepartment of Geography and Environmental Development, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Heike Luttmann-GibsonDepartment of Environmental Health, Harvard School of Public Health, Boston, MA, USA.
Diane R GoldDepartment of Environmental Health, Harvard School of Public Health, Boston, MA, USA.
Emily OkenObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Joel D SchwartzDepartment of Environmental Health, Harvard School of Public Health, Boston, MA, USA.
Ben-Gurion University of the Negev · ILBoston Children's Hospital · USBrigham and Women's Hospital · USHarvard University · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Prenatal environmental determinants of health in young adulthood: a lifecourse approachR01HD034568 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI Marie-France Hivert, Emily Oken · 1998 to 2026
$20.6M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
CAREER DEVELOPMENT IN DIABETES RESEARCH FOR PEDIATRIC ENDOCRINOLOGISTSK12DK094721 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI LAFFEL, LORI M, WHITE, MORRIS F. · 2011 to 2021
$6.3M
The Fetal and Childhood Environment, Oxidative Balance, Inflammation and AsthmaR01AI102960 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLD, DIANE R, OKEN, EMILY · 2013 to 2017
$4.0M
Patient-oriented Research in Maternal Perinatal Overnutrition and Child AdiposityK24HD069408 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI OKEN, EMILY · 2011 to 2015
$844k
Air Pollution Exposure during Pregnancy, Maternal Glycemia, and OffspringGrowthK23ES024803 · NIEHS · MAINEHEALTH · PI FLEISCH, ABBY · 2015 to 2019
$835k
NIAID NIH HHS R01 AI102960NICHD NIH HHS K24 HD069408NICHD NIH HHS K24HD069408NICHD NIH HHS R01 HD034568NIDDK NIH HHS K12 DK094721NIDDK NIH HHS K12DK094721NIDDK NIH HHS P30 DK092924NIDDK NIH HHS P30DK092924NIEHS NIH HHS ES000002NIEHS NIH HHS K23 ES024803NIEHS NIH HHS K23ES024803NIEHS NIH HHS P30 ES000002
6 · The paper itself

Abstract

backgroundRodent and human studies suggest an association between air pollution exposure and type 2 diabetes mellitus, but the extent to which air pollution is associated with gestational diabetes mellitus (GDM) is less clear.

methodsWe used the Massachusetts Registry of Vital Records to study primiparous women pregnant from 2003-2008 without pre-existing diabetes. We used satellite-based spatiotemporal models to estimate first and second trimester residential particulate (PM2.5) exposure and geographic information systems to estimate neighborhood traffic density. We obtained GDM status from birth records. We performed logistic regression analyses adjusted for sociodemographics on the full cohort and after stratification by maternal age and smoking habits.

resultsOf 159,373 women, 5,381 (3.4 %) developed GDM. Residential PM2.5 exposure ranged 1.3-19.3 μg/m(3) over the second trimester. None of the exposures were associated with GDM in the full cohort [e.g. OR 0.99 (95 % CI: 0.95, 1.03) for each interquartile range (IQR) increment in second trimester PM2.5]. There were also no consistent associations after stratification by smoking habits. When the cohort was stratified by maternal age, women less than 20 years had 1.36 higher odds of GDM (95 % CI: 1.08, 1.70) for each IQR increment in second trimester PM2.5 exposure.

conclusionsAlthough we found no evidence of an association between air pollution exposure and GDM among all women in our study, greater exposure to PM2.5 during the second trimester was associated with GDM in the youngest age stratum.

Indexed as

AdultAge FactorsAir PollutantsAir PollutionCohort StudiesDiabetes, GestationalFemaleHumansMassachusettsMaternal ExposureParticulate MatterPregnancyPregnancy Trimester, SecondYoung AdultAir PollutantsParticulate Matter

Identifiers

PMID26911579
PMCPMC4765142
OpenAlexW2281862582

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.