Evidence map›Paper›PMID 26911532›Full record

Trial reportJournal of human hypertension2017

Family member-based supervision of patients with hypertension: a cluster randomized trial in rural China.

Y Shen, X Peng, M Wang, X Zheng, G Xu, L Lü, K Xu, B Burstrom, K Burstrom, J Wang

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of human hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Y ShenDepartment of Gastrointestinal Surgery, Aoyoung Hospital, Zhangjiagang, China.
X PengDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
M WangDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
X ZhengDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
G XuDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
L LüDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.
K XuDepartment of Social Medicine and Health Education, School of Public Health, Nanjing Medical University, Nanjing, China.
B BurstromDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
K BurstromDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
J WangDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Empirical evidence has suggested that social support from family can help patients take their medicines correctly. This study aims to evaluate the role of a family member-based supervision package in the management of hypertension using a cluster randomized trial in rural China. We recruited patients with hypertension from four villages in Yangzhong and randomly allocated them to the control group (n=288) and the intervention group (n=266). A family member-based supervision package was applied to the intervention group, while the usual service was applied to the controls. Patients were followed for 12 months and completed face-to-face interviews at the end of 6 and 12 months. The primary outcomes were patients' medication adherence and frequency of blood pressure measurement. Secondary outcomes included changes in blood pressure, altered risk behaviours and occurrence of hypertension-related complications. To control for the effects of cluster randomization, multilevel mixed-effects regression models were used to compare group changes. We observed that the intervention improved patients' blood pressure measurement frequency (OR: 9.00, 95% CI: 4.52-17.91) and adherence to antihypertensive treatment (OR: 1.74, 95% CI: 0.91-3.32). Its effect on the blood pressure control rate was significant at the mid-term investigation (OR: 0.67, 95% CI: 0.40-0.93), but the long-term effect was not significant (OR: 0.89, 95% CI: 0.64-1.26). After 6 months of intervention, either systolic or diastolic blood pressure was significantly decreased in the intervention group. However, this difference was not significant at the final investigation. Findings from this study revealed that the family member-based supervised therapy may have positive effects on patients' adherence to blood monitoring and hypertensive medications.

Indexed as

Medication AdherenceAgedAntihypertensive AgentsBlood Pressure Monitoring, AmbulatoryFamily RelationsFemaleHumansHypertensionMaleMiddle AgedSocial SupportAntihypertensive Agents

Identifiers

PMID26911532
PMCPMC5144121

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.