Evidence map›Paper›PMID 26911438›Full record

Trial reportJournal of neuroengineering and rehabilitation2016

Effects of virtual reality-based rehabilitation on distal upper extremity function and health-related quality of life: a single-blinded, randomized controlled trial.

Joon-Ho Shin, Mi-Young Kim, Ji-Yeong Lee, Yu-Jin Jeon, Suyoung Kim, Soobin Lee, Beomjoo Seo, Younggeun Choi

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of neuroengineering and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 77 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 16 pooled it
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02029651 naunknown statusnot on this map

Effects of Novel Game Rehabilitation System (E-glove System) on Upper Extremity Function of Patients With Stroke :Randomized Controlled Trial

TypeinterventionalSponsorNational Rehabilitation Center, Seoul, KoreaRan2014Enrolled59ConditionsStrokeArmsE-glove system, Conventional occupational therapy
NCT07378085 nacompletednot on this mapstarted 2023, after this paper: background citation

The Impact of Virtual Reality Games on Upper Extremity Function, Activity, and Participation in Hemiplegic Patients: A Randomized Controlled Trial

TypeinterventionalSponsorGaziosmanpasa Research and Education HospitalRan2023 to 2023Enrolled40ConditionsUpper Extremity Hemiplegia, Stroke, Virtual Reality Based TherapyArmsconventional rehabilitation, leap motion based virtual reality rehabilitation
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 16 syntheses or guidelines pooled it, 216 citations in OpenAlex.

  1. Efficacy of digital health technologies as adjunctive functional training in occupational therapy for stroke rehabilitation: a meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  4. Virtual reality for stroke rehabilitation.The Cochrane database of systematic reviews · 2025
    Pooled it
  5. Virtual Reality Therapy for Upper Limb Motor Impairments in Patients With Stroke: A Systematic Review and Meta-Analysis.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025
    Pooled it
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  11. Robot-assisted distal training improves upper limb dexterity and function after stroke: a systematic review and meta-regression.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Pooled it
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  13. Serious games for upper limb rehabilitation after stroke: a meta-analysis.Journal of neuroengineering and rehabilitation · 2021
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  16. Virtual reality for stroke rehabilitation.The Cochrane database of systematic reviews · 2017
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Joon-Ho ShinNational Rehabilitation Center, Ministry of Health and Welfare, Seoul, Korea. asfreelyas@gmail.com.
Mi-Young KimNational Rehabilitation Center, Ministry of Health and Welfare, Seoul, Korea. ocielo@hanmail.net.
Ji-Yeong LeeNational Rehabilitation Center, Ministry of Health and Welfare, Seoul, Korea. wldud3575@hanmail.net.
Yu-Jin JeonNational Rehabilitation Center, Ministry of Health and Welfare, Seoul, Korea. eie0305@naver.com.
Suyoung KimDepartment of Law, Hanyang University, Seoul, Korea. law30803@gmail.com.
Soobin LeeNeofect, Yong-in, Korea. sb.lee@neofect.com.
Beomjoo SeoSchool of Games, Hongik University, Seoul, Korea. bseo@hongik.ac.kr.
Younggeun ChoiNeofect, Yong-in, Korea. younggch@dankook.ac.kr.
Ministry of Health and Welfare · KRDankook University · KRHanyang University · KRHongik University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVirtual reality (VR)-based rehabilitation has been reported to have beneficial effects on upper extremity function in stroke survivors; however, there is limited information about its effects on distal upper extremity function and health-related quality of life (HRQoL). The purpose of the present study was to examine the effects of VR-based rehabilitation combined with standard occupational therapy on distal upper extremity function and HRQoL, and compare the findings to those of amount-matched conventional rehabilitation in stroke survivors.

methodsThe present study was a single-blinded, randomized controlled trial. The study included 46 stroke survivors who were randomized to a Smart Glove (SG) group or a conventional intervention (CON) group. In both groups, the interventions were targeted to the distal upper extremity and standard occupational therapy was administered. The primary outcome was the change in the Fugl-Meyer assessment (FM) scores, and the secondary outcomes were the changes in the Jebsen-Taylor hand function test (JTT), Purdue pegboard test, and Stroke Impact Scale (SIS) version 3.0 scores. The outcomes were assessed before the intervention, in the middle of the intervention, immediately after the intervention, and 1 month after the intervention.

resultsThe improvements in the FM (FM-total, FM-prox, and FM-dist), JTT (JTT-total and JTT-gross), and SIS (composite and overall SIS, SIS-social participation, and SIS-mobility) scores were significantly greater in the SG group than in the CON group.

conclusionsVR-based rehabilitation combined with standard occupational therapy might be more effective than amount-matched conventional rehabilitation for improving distal upper extremity function and HRQoL.

trial registrationThis study is registered under the title "Effects of Novel Game Rehabilitation System on Upper Extremity Function of Patients With Stroke" and can be located in https://clinicaltrials.gov with the study identifier NCT02029651 .

Indexed as

Stroke RehabilitationUser-Computer InterfaceAgedAlgorithmsFemaleHumansMaleMiddle AgedOccupational TherapyQuality of LifeSingle-Blind MethodTreatment OutcomeUpper ExtremityVideo Games

Identifiers

PMID26911438
PMCPMC4765099
OpenAlexW2278938864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.