Evidence map›Paper›PMID 26911397›Full record

Trial reportBMC psychiatry2016

Adherence therapy versus routine psychiatric care for people with schizophrenia spectrum disorders: a randomised controlled trial.

Wai Tong Chien, Jolene Mui, Richard Gray, Eric Cheung

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01780116 phase1 / phase2completednot on this map

An Evaluation of the Effectiveness of Adherence Therapy for Schizophrenia: A Randomized Controlled Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2013 to 2016Enrolled134ConditionsSchizophrenia, Schizophreniform Disorder, Schizoaffective DisorderArmsAdherence therapy
NCT06192602 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Testing the Effectiveness of an Acceptance-based Adherence Therapy for People With Recent-onset Psychosis: A Randomized Controlled Trial

TypeinterventionalSponsorChinese University of Hong KongRan2023 to 2027Enrolled126ConditionsEarly Psychosis, Psychotic DisordersArmsAIM_AT, CPG, TAU
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Wai Tong ChienSchool of Nursing, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, S.A.R., China. wai.tong.chien@polyu.edu.hk.
Jolene MuiCastle Peak Hospital, Tuen Mun, New Territories, Hong Kong, S.A.R., China.
Richard GrayHamad Medical Corporation, P.O. Box 3050, Doha, Qatar.
Eric CheungCastle Peak Hospital, Tuen Mun, New Territories, Hong Kong, S.A.R., China.
Castle Peak Hospital · CNHamad Medical Corporation · QAHong Kong Polytechnic University · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent practice guidelines for schizophrenia care recommend that antipsychotic medication is essential for patients' long-term maintenance treatment but their non-adherence to this medication is still a main obstacle to relapse prevention. This study evaluated the effects of a motivational-interviewing-based adherence therapy for people with schizophrenia spectrum disorders.

methodsThis randomised controlled trial was conducted with 134 outpatients with schizophrenia spectrum disorders; 67 of them received a six-session adherence therapy (in addition to usual care) and 67 received usual psychiatric care alone. Participants' outcome measures included symptom severity, medication adherence, hospitalisation rates, insight into illness/treatment, and functioning.

resultsThe adherence therapy group reported significantly greater improvements in symptom severity (p < 0.003), insight into illness/treatment (p < 0.001), functioning (p < 0.005), duration of re-hospitalisations (p < 0.005), and medication adherence (p < 0.005) over 18 months follow-up, when compared with usual care alone.

conclusionsMotivational-interviewing-based adherence therapy can be an effective approach to treatment for people with early stage of schizophrenia who poorly adhere to medication regimen.

trial registrationClinicalTrials.gov NCT01780116, registration date January 29, 2013.

Indexed as

Drug MonitoringAdultAntipsychotic AgentsCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedMotivational InterviewingPatient Education as TopicPsychotherapyPsychotherapy, GroupSchizophreniaSchizophrenic PsychologyTreatment OutcomeAntipsychotic Agents

Identifiers

PMID26911397
PMCPMC4766670
OpenAlexW2287987347

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.