ArticleMaternal and child health journal2016
Physical Activity During Pregnancy and Subsequent Risk of Preeclampsia and Gestational Hypertension: A Case Control Study.
Article in Maternal and child health journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Sedentary behavior during pregnancy and risk of pre-eclampsia and/or gestational hypertension: A systematic review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Pooled it
- eHealth and Hypertensive Disorders of Pregnancy: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Selective serotonin reuptake inhibitors and preeclampsia: A quality assessment and meta-analysis.Pregnancy hypertension · 2022Pooled it
- Occupational Risk Factors and Hypertensive Disorders in Pregnancy: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- The metabolic implications of maternal exercise: effects on pregnant women and their offspring.Frontiers in nutrition · 2026Review
- Associations of prenatal exposure to residential greenspace and active living environments with cerebral palsy: A population-based cohort study in Ontario, Canada.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Dietary patterns during pregnancy and maternal and birth outcomes in women with type 1 diabetes: the Environmental Determinants of Islet Autoimmunity (ENDIA) study.Diabetologia · 2024Article
- Prevention of Pregnancy Complications Using a Multimodal Lifestyle, Screening, and Medical Model.Journal of clinical medicine · 2024Review
- Early Prediction of Hypertensive Diseases of Pregnancy by Using Combined Screening Methods in a Rural Population.Cureus · 2023Article
- The relationship between physical activity in early pregnancy and hypertensive disorders of pregnancy: a cohort study in Chinese women.World journal of emergency medicine · 2023Article
- Design and validation of theory-based perceptions concerning the physical literacy questionnaire for pregnant women (P2LQ-PW).BMC public health · 2022Article
- Alcohol Intake and Hypertensive Disorders of Pregnancy: A Negative Control Analysis in the ALSPAC Cohort.Journal of the American Heart Association · 2022Article
- Observational
- Gestational Diabetes and Hypertensive Disorders of Pregnancy by Maternal Birthplace.American journal of preventive medicine · 2022Article
- Maternal Physical Activity at Term and Spontaneous Labor: A Case-Crossover Study.Journal of physical activity & health · 2022Article
- Effect of initial COVID-19 outbreak during first trimester on pregnancy outcome in Wuxi, China.BMC pregnancy and childbirth · 2022Article
- Occupational exposure to whole-body vibrations and pregnancy complications: a nationwide cohort study in Sweden.Occupational and environmental medicine · 2020Article
- I-ACT: Integrated study on effect of Activity on ComplicaTions in pregnancy: study protocol of a multiethnic prospective cohort study.BMJ open · 2019Article
- Risk factors for the development of new-onset and persistent postpartum preeclampsia: A case-control study in Ghana.Women's health (London, England)Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
objectivePhysical activity (PA) is hypothesized to reduce the risk of preeclampsia, but few epidemiologic studies have simultaneously evaluated leisure time PA (LTPA), sedentary activity, occupational activity, and non-occupational, non-leisure time PA. Thus, we assessed the independent and combined effects of these different types of PA during pregnancy on preeclampsia and gestational hypertension risk.
methodsPreeclamptic (n = 258), gestational hypertensive (n = 233), and normotensive (n = 182) women identified from Iowa live birth records (2002-2005) were participants in Study of Pregnancy Hypertension in Iowa. Disease status was verified by medical chart review. All PA exposures were self-reported. Multinomial logistic regression was used to test for associations between various PA types and risk for preeclampsia or gestational hypertension.
resultsAfter adjusting for prepregnancy BMI, increasing levels of LTPA were associated with a reduced risk of preeclampsia (trend, p = 0.02). Additionally, increasing amount of time spent active each day was associated with decreasing risks for preeclampsia (adjusted, trend; p = 0.03). Increasing amount of time spent sitting per day was associated with an increasing risk of preeclampsia (adjusted, trend; p = 0.10). Women whose activity averaged >8.25 h per day were at a significantly reduced risk of preeclampsia relative to women active <4.2 h per day (adjusted OR 0.58, 95 % CI 0.36, 0.95). Most analyses evaluating the risk of gestational hypertension yielded null results or results that trended in the direction opposite of the preeclampsia results.
conclusionConsistent with previous studies, these data suggest increasing PA during pregnancy may reduce preeclampsia risk while increasing levels of sedentary activity may increase disease risk.
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Registered trials
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