ArticlePloS one2016
Prediction of Fitness to Drive in Patients with Alzheimer's Dementia.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- [Current Evidence for Assessing Fitness to Drive of People with Cognitive Impairment: A Systematic Review].Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) · 2023Pooled it
- Driving and Alzheimer's dementia or mild cognitive impairment: a systematic review of the existing guidelines emphasizing on the neurologist's role.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Pooled it
- Driving with Motor Neuron Disease: Disease-Specific Considerations, Multi-Domain Assessments and Support Strategies.Brain sciences · 2026Review
- Enhancing road safety: In-vehicle sensor analysis of cognitive impairment in older drivers.Multimedia tools and applications · 2025Article
- Driving Assessment for Persons with Dementia: How and when?Aging and disease · 2023Review
- Olfactory discrimination and identification as prognostic markers of fitness-to-drive in older drivers.Scientific reports · 2022Article
- Evaluation of the Glymphatic System With Diffusion Tensor Imaging-Along the Perivascular Space in Cancer Pain.Frontiers in neuroscience · 2022Article
- The SIMARD-MD is not an Effective Driver Screening Tool for Determining Fitness-To-Drive.Canadian geriatrics journal : CGJ · 2021Article
- Predicting On-Road Driving Skills, Fitness to Drive, and Prospective Accident Risk in Older Drivers and Drivers with Mild Cognitive Impairment: The Importance of Non-Cognitive Risk Factors.Journal of Alzheimer's disease : JAD · 2021Article
- Assessing Fitness-To-Drive among Older Drivers: A Comparative Analysis of Potential Alternatives to on-Road Driving Test.International journal of environmental research and public health · 2020Article
- Feasibility and Validity of a Low-Cost Racing Simulator in Driving Assessment after Stroke.Geriatrics (Basel, Switzerland) · 2020Article
- The MMSE should not be the sole indicator of fitness to drive in mild Alzheimer's dementia.Acta neurologica Belgica · 2018Article
- Agreement of driving simulator and on-road driving performance in patients with binocular visual field loss.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018Article
- Adherence to driving cessation advice given to patients with cognitive impairment and consequences for mobility.BMC geriatrics · 2018Article
- Article
- Driving Ability in Alzheimer Disease Spectrum: Neural Basis, Assessment, and Potential Use of Optic Flow Event-Related Potentials.Frontiers in neurology · 2018Review
- A novel low-cost solution for driving assessment in individuals with and without disabilities.Applied ergonomics · 2017Article
- Driving with a neurodegenerative disorder: an overview of the current literature.Journal of neurology · 2017Review
- Ethical Challenges in Geriatric Psychiatry.Focus (American Psychiatric Publishing) · 2017Article
- Driving and dementia: a clinical update for mental health professionals.Evidence-based mental health · 2016Article
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The number of patients with Alzheimer's disease (AD) is increasing and so is the number of patients driving a car. To enable patients to retain their mobility while at the same time not endangering public safety, each patient should be assessed for fitness to drive. The aim of this study is to develop a method to assess fitness to drive in a clinical setting, using three types of assessments, i.e. clinical interviews, neuropsychological assessment and driving simulator rides. The goals are (1) to determine for each type of assessment which combination of measures is most predictive for on-road driving performance, (2) to compare the predictive value of clinical interviews, neuropsychological assessment and driving simulator evaluation and (3) to determine which combination of these assessments provides the best prediction of fitness to drive. Eighty-one patients with AD and 45 healthy individuals participated. All participated in a clinical interview, and were administered a neuropsychological test battery and a driving simulator ride (predictors). The criterion fitness to drive was determined in an on-road driving assessment by experts of the CBR Dutch driving test organisation according to their official protocol. The validity of the predictors to determine fitness to drive was explored by means of logistic regression analyses, discriminant function analyses, as well as receiver operating curve analyses. We found that all three types of assessments are predictive of on-road driving performance. Neuropsychological assessment had the highest classification accuracy followed by driving simulator rides and clinical interviews. However, combining all three types of assessments yielded the best prediction for fitness to drive in patients with AD with an overall accuracy of 92.7%, which makes this method highly valid for assessing fitness to drive in AD. This method may be used to advise patients with AD and their family members about fitness to drive.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.