ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2016
ULTRASTRUCTURAL CHANGES IN Schistosoma mansoni MALE WORMS AFTER in vitro INCUBATION WITH THE ESSENTIAL OIL OF Mentha x villosa Huds.
Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Antiparasitic Activity of Chalepensin and Graveoline Isolated fromPathogens (Basel, Switzerland) · 2025Article
- In Vivo Antischistosomicidal and Immunomodulatory Effects of Dietary Supplementation withJournal of xenobiotics · 2024Article
- Therapeutic Potential of Natural Products in the Treatment ofMolecules (Basel, Switzerland) · 2023Review
- Antischistosomal effects ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Article
- Human serum activates the tegument of female schistosomes and supports recovery from Praziquantel.Parasitology research · 2021Article
- Antiparasitic effects of ethanolic extracts ofParasitology · 2020Article
- Inactivation of Spoilage Yeasts byFrontiers in microbiology · 2018Article
- Ultrastructural alterations in Schistosoma mansoni juvenile and adult male worms after in vitro incubation with primaquine.Memorias do Instituto Oswaldo Cruz · 2017Article
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Authors and funding
13 authors.
Funding
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Abstract
introductionThe essential oil Mentha x villosa (MVEO) has a wide range of actions, including antibacterial, antifungal, antiprotozoal and schistosomicidal actions. The present study aimed to investigate the ultrastructural changes of MVEO on the tegument of adult Schistosoma mansoni. MATERIALS AND
methodsDifferent concentrations of MVEO were tested on S. mansoni adult worms in vitro. Ultrastructural changes on the tegument of these adult worms were evaluated using scanning electron microscopy (SEM) and transmission electron microscopy (TEM).
resultsThe MVEO caused the death of all worms at 500 μg mL(-1) after 24 h. After 24h of 500 μg mL(-1) MVEO treatment, bubble lesions were observed over the entire body of worms and they presented loss of tubercles in some regions of the ventral portion. In the evaluation by TEM, S. mansoni adult worms treated with MVEO, 500 μg mL(-1), presented changes in the tegument and vacuoles in the syncytial matrix region. Glycogen granules close to the muscle fibers were visible.
conclusionThe ability of MVEO to cause extensive ultrastructural damage to S. mansoni adult worms correlates with its schistosomicidal effects and confirms earlier findings with S. mansoni.
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