Evidence map›Paper›PMID 26909477›Full record

ArticleArchives of endocrinology and metabolism2016

Is 131I ablation necessary for patients with low-risk papillary thyroid carcinoma and slightly elevated stimulated thyroglobulin after thyroidectomy?

Pedro Weslley Rosario, Gabriela Franco Mourão

Abstract read
In one paragraph

Article in Archives of endocrinology and metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Iodine-131: An Effective Method for Treating Lymph Node Metastases of Differentiated Thyroid Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2016
    Article
  3. Radioiodine for thyroid cancer: sometimes, less is best.Archives of endocrinology and metabolism · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Pedro Weslley RosarioSanta Casa de Belo Horizonte, Belo Horizonte, MG, Brazil.
Gabriela Franco MourãoSanta Casa de Belo Horizonte, Belo Horizonte, MG, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis prospective study evaluated the recurrence rate in low-risk patients with papillary thyroid cancer (PTC) who presented slightly elevated thyroglobulin (Tg) after thyroidectomy and who did not undergo ablation with131I. SUBJECTS AND

methodsThe study included 53 low-risk patients (nonaggressive histology; pT1b-3, cN0pNx, M0) with slightly elevated Tg after thyroidectomy (> 1 ng/mL, but ≤ 5 ng/mL after levothyroxine withdrawal or ≤ 2 ng/mL after recombinant human TSH).

resultsThe time of follow-up ranged from 36 to 96 months. Lymph node metastases were detected in only one patient (1.9%). Fifty-two patients continued to present negative neck ultrasound. None of these patients without apparent disease presented an increase in Tg.

conclusionsLow-risk patients with PTC who present slightly elevated Tg after thyroidectomy do not require ablation with 131I.

Indexed as

Neoplasm Recurrence, LocalThyroidectomyAdolescentAdultAgedAged, 80 and overCarcinomaCarcinoma, PapillaryFemaleFollow-Up StudiesHumansIodine RadioisotopesLymphatic MetastasisMaleMiddle AgedProspective StudiesIodine RadioisotopesThyroglobulinThyrotropin Alfa

Identifiers

PMID26909477
PMCPMC10118909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.