ArticleAvicenna journal of phytomedicine
Effect of Malva sylvestris cream on burn injury and wounds in rats.
Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 42 citations in OpenAlex.
- The Effect of Malva Sylvestris Cream on Episiotomy Pain and Healing: A Randomized Controlled Clinical Trial.International journal of community based nursing and midwifery · 2022Trial
- Advancements in Herbal Drug Loaded Nanoparticulate System for Antimicrobial Effect.Current topics in medicinal chemistry · 2025Review
- Comparison of the Efficacy of TopicalMedical journal of the Islamic Republic of Iran · 2025Article
- Phytochemistry and Pharmacological Activity ofCombinatorial chemistry & high throughput screening · 2024Review
- Effects of dose-dependent chronic caffeine consumption in a rat burn wound model: Histopathological and immunohistochemical evaluation.Iranian journal of basic medical sciences · 2024Article
- Synthesis and characterization of Hyaluronic Acid (HA) modified polymeric composite for effective treatment of wound healing by transdermal drug delivery system (TDDS).Scientific reports · 2023Article
- The Potential of Medicinal Plants and Natural Products in the Treatment of Burns and Sunburn-A Review.Pharmaceutics · 2023Review
- A Comprehensive Review of Natural Compounds for Wound Healing: Targeting Bioactivity Perspective.International journal of molecular sciences · 2022Review
- Phytochemistry and Biological Activity of Medicinal Plants in Wound Healing: An Overview of Current Research.Molecules (Basel, Switzerland) · 2022Review
- Arbutin Inhibited Heat Stress-Induced Apoptosis and Promoted Proliferation and Migration of Heat-Injured Dermal Fibroblasts and Keratinocytes by Activating PI3K/AKT Signaling Pathway.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Advantages of Hyaluronic Acid and Its Combination with Other Bioactive Ingredients in Cosmeceuticals.Molecules (Basel, Switzerland) · 2021Review
- Preparation of Polyurethane/Pluronic F127 Nanofibers Containing Peppermint Extract Loaded Gelatin Nanoparticles for Diabetic Wounds Healing: Characterization, In Vitro, and In Vivo Studies.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials.Antioxidants (Basel, Switzerland) · 2020Review
- Efficacy of topical application of standardized extract ofJournal of traditional and complementary medicine · 2019Article
- Scientific Evaluation of Medicinal Plants Used for the Treatment of Cervicitis (Qorohe- Rahem) in Iranian Traditional Medicine.Iranian journal of pharmaceutical research : IJPR · 2019Article
- Effects of herbal ointment containing the leaf extracts of Madeira vine (Veterinary world · 2017Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesBurn injury is one of the most health-threatening problems in the world. Malva sylvestris (M. sylvestris) flowers have a high mucilage content and are used as a remedy for cut wound and dermal infected wounds in Iranian folklore Medicine. The purpose of this study was to investigate the effect of M. sylvestris cream on the second degree burn injury in rats. MATERIALS AND
methodsFive groups of 10 rats per group were burned with hot metal plate. Animals were administrated divided as control, normal saline, standard silver sulfadiazine 1% (SSD), 5% M. sylvestris, and 10% M. sylvestris into separate groups. Wound area, percentage of wound contraction, and histological and bacteriological assessments were evaluated.
resultsWound sizes were not significantly different among groups on 1(st) and 3(rd) days after burn injury, while they were significantly different among groups after 7(th) day post-burn injury. The average areas of wounds on the 15(th) day were 7.5±2.9, 6.7±2, 10.5±1.6, 4.7±2, and 4.5±2 cm(2) for base cream, normal saline, SSD, 5% M. sylvestris, and 10% M. sylvestris, respectively. The results of histology exhibited well-formed horizontally-oriented collagen fibers in MS topical treatment groups. Microorganisms existed in the SSD group were most probably Staphilococcus epidermitis and for NS group were staphylococcus saprophiteccus.
conclusionM. sylvestris cream improved histological changes of tissue components in the process of healing when compared with SSD cream. Therefore, it can be used as a topical treatment agent for burn wound.
Indexed as
Identifiers
26909337PMC4587603W1515835307What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.