Evidence map›Paper›PMID 26909109›Full record

ArticleTheranostics2016

Imalytics Preclinical: Interactive Analysis of Biomedical Volume Data.

Felix Gremse, Marius Stärk, Josef Ehling, Jan Robert Menzel, Twan Lammers, Fabian Kiessling

Abstract read
In one paragraph

Article in Theranostics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed.

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  11. Image-Derived Blood Normalization of Antibody-Based TREM2 PET in Mouse Models of Amyloidosis and Myocardial Infarction.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  12. Article
  13. Article
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  17. The NaAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  18. Article
  19. Article
  20. Single Chelator-Minibody Theranostic Agents forJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Felix Gremse1. Experimental Molecular Imaging, University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Marius Stärk1. Experimental Molecular Imaging, University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Josef Ehling1. Experimental Molecular Imaging, University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Jan Robert Menzel2. Computer Graphics and Multimedia, RWTH Aachen University, Aachen, Germany.
Twan Lammers1. Experimental Molecular Imaging, University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Fabian Kiessling1. Experimental Molecular Imaging, University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.

Funding

European Research Council 309495
6 · The paper itself

Abstract

A software tool is presented for interactive segmentation of volumetric medical data sets. To allow interactive processing of large data sets, segmentation operations, and rendering are GPU-accelerated. Special adjustments are provided to overcome GPU-imposed constraints such as limited memory and host-device bandwidth. A general and efficient undo/redo mechanism is implemented using GPU-accelerated compression of the multiclass segmentation state. A broadly applicable set of interactive segmentation operations is provided which can be combined to solve the quantification task of many types of imaging studies. A fully GPU-accelerated ray casting method for multiclass segmentation rendering is implemented which is well-balanced with respect to delay, frame rate, worst-case memory consumption, scalability, and image quality. Performance of segmentation operations and rendering are measured using high-resolution example data sets showing that GPU-acceleration greatly improves the performance. Compared to a reference marching cubes implementation, the rendering was found to be superior with respect to rendering delay and worst-case memory consumption while providing sufficiently high frame rates for interactive visualization and comparable image quality. The fast interactive segmentation operations and the accurate rendering make our tool particularly suitable for efficient analysis of multimodal image data sets which arise in large amounts in preclinical imaging studies.

Indexed as

SoftwareAnimalsHumansImage Processing, Computer-AssistedMultimodal ImagingGPU ProcessingInteractive SegmentationMedical Image AnalysisMultimodal ImagingSegmentation RenderingUndo/Redo

Identifiers

PMID26909109
PMCPMC4737721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.