ArticleFrontiers in plant science2016
Identification and Characterization of a Glyoxalase I Gene in a Rapeseed Cultivar with Seed Thermotolerance.
Article in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Integrating multiomic resources and gene expression studies to identify candidates for engineering climate-resilientFrontiers in plant science · 2026Review
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- The Maize GeneInternational journal of molecular sciences · 2024Article
- Identification, Evolutionary Dynamics, and Gene Expression Patterns of thePlants (Basel, Switzerland) · 2024Article
- Role of methylglyoxal and glyoxalase in the regulation of plant response to heavy metal stress.Plant cell reports · 2024Review
- MeGLYI-13, a Glyoxalase I Gene in Cassava, Enhances the Tolerance of Yeast andPlants (Basel, Switzerland) · 2023Article
- Genome-Wide Identification and Functional Characterization of Stress Related Glyoxalase Genes inInternational journal of molecular sciences · 2023Article
- Genetic and Physiological Responses to Heat Stress inFrontiers in plant science · 2022Review
- Comparative Proteomics at the Critical Node of Vigor Loss in Wheat Seeds Differing in Storability.Frontiers in plant science · 2021Article
- Salt-Tolerant Phenomena, Sequencing and Characterization of aPlants (Basel, Switzerland) · 2020Article
- An Integration of Genome-Wide Association Study and Gene Co-expression Network Analysis Identifies Candidate Genes of Stem Lodging-Related Traits inFrontiers in plant science · 2018Article
- Genome-wide analysis and expression profiles of glyoxalase gene families in Chinese cabbage (Brassica rapa L).PloS one · 2018Article
- Synergistic inhibition of colon cancer growth by the combination of methylglyoxal and silencing of glyoxalase I mediated by the STAT1 pathway.Oncotarget · 2017Article
- Characteristic Variations and Similarities in Biochemical, Molecular, and Functional Properties of Glyoxalases across Prokaryotes and Eukaryotes.International journal of molecular sciences · 2017Review
- Genome-Wide Association Mapping Reveals the Genetic Control Underlying Branch Angle in Rapeseed (Frontiers in plant science · 2017Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glyoxalase I (GLYI) is a ubiquitous enzyme in all organisms that catalyzes the conversion of the potent cytotoxin methylglyoxal to S-D-lactoylglutathione. Although many reports suggest the importance of GLYI in the plant response to stress, its function in seeds requires further study. Here, we identified a heat-induced GLYI from Brassica napus seeds, BnGLYI, using a comparative proteomics approach. Two-dimensional gel analyses revealed that BnGLYI protein expression upon heat treatment was significantly elevated in thermotolerant seeds but was diminished in heat-sensitive seeds. The BnGLYI-2 and BnGLYI-3 genes from the heat-sensitive and thermotolerant cultivars, respectively, were characterized, and analyzed. Only two amino acid residue variations were found between the amino acid sequences of the two genes. Moreover, overexpressing BnGLYI-3 in yeast cells enhanced tolerance to heat and cold stress and significantly increased GLYI activity compared to overexpressing BnGLYI-2. In addition, BnGLYI-3 transformants showed enhanced superoxide dismutase activities under heat and cold treatment, whereas these activities were diminished for BnGLYI-2 transformants. Taken together, these results indicate that overexpression of the BnGLYI-3 gene imparts thermotolerance and cold tolerance in yeast and that the variations in BnGLYI-3 may play an important role in the responses to temperature stresses.
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