Evidence map›Paper›PMID 26909038›Full record

ArticleFrontiers in aging neuroscience2016

Increased Hippocampus-Medial Prefrontal Cortex Resting-State Functional Connectivity and Memory Function after Tai Chi Chuan Practice in Elder Adults.

Jing Tao, Jiao Liu, Natalia Egorova, Xiangli Chen, Sharon Sun, Xiehua Xue, Jia Huang, Guohua Zheng, Qin Wang, Lidian Chen and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 13 syntheses or guidelines pooled it.

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  10. The Effects of Mind-Body Exercise on Cognitive Performance in Elderly: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2018
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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jing TaoCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China; Fujian Key Laboratory of Rehabilitation of Technology, Fuzhou, China; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Jiao LiuCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine , Fuzhou , China.
Natalia EgorovaDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School , Boston, MA , USA.
Xiangli ChenThe School of Social and Political Science, University of Edinburgh , Edinburgh , UK.
Sharon SunDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School , Boston, MA , USA.
Xiehua XueAffiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine , Fuzhou , China.
Jia HuangCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China; Fujian Key Laboratory of Rehabilitation of Technology, Fuzhou, China.
Guohua ZhengCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine , Fuzhou , China.
Qin WangCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine , Fuzhou , China.
Lidian ChenCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China; Fujian Key Laboratory of Rehabilitation of Technology, Fuzhou, China.
Jian KongDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School , Boston, MA , USA.

Funding

The Role of Context Effect in Acupuncture Treatment of Low Back/J.KongP01AT006663 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI HIRSCHTICK, RANDY L, ROSEN, BRUCE R · 2011 to 2017
$10.0M
Neuromodulation of placebo and nocebo effectsR01AT008563 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI KONG, JIAN · 2015 to 2019
$3.9M
The Neurobiology of Placebo and Nocebo Effects: A Brain Imaging StudyR01AT006364 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI KONG, JIAN · 2011 to 2015
$3.6M
Neural dynamics of directly and indirectly conditioned placebo/nocebo effectR21AT008707 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI KONG, JIAN · 2016 to 2017
$479k
NCCIH NIH HHS P01 AT006663NCCIH NIH HHS R01 AT006364NCCIH NIH HHS R01 AT008563NCCIH NIH HHS R21 AT008707
6 · The paper itself

Abstract

Previous studies provide evidence that aging is associated with the decline of memory function and alterations in the hippocampal (HPC) function, including functional connectivity to the medial prefrontal cortex (mPFC). In this study, we investigated if longitudinal (12-week) Tai Chi Chuan and Baduanjin practice can improve memory function and modulate HPC resting-state functional connectivity (rs-FC). Memory function measurements and resting-state functional magnetic resonance imaging (rs-fMRI) were applied at the beginning and the end of the experiment. The results showed that (1) the memory quotient (MQ) measured by the Wechsler Memory Scale-Chinese Revision significantly increased after Tai Chi Chuan and Baduanjin practice as compared with the control group, and no significant difference was observed in MQ between the Tai Chi Chuan and Baduanjin groups; (2) rs-FC between the bilateral hippocampus and mPFC significantly increased in the Tai Chi Chuan group compared to the control group (also in the Baduanjin group compared to the control group, albeit at a lower threshold), and no significant difference between the Tai Chi Chuan and Baduanjin groups was observed; (3) rs-FC increases between the bilateral hippocampus and mPFC were significantly associated with corresponding memory function improvement across all subjects. Similar results were observed using the left or right hippocampus as seeds. Our results suggest that both Tai Chi Chuan and Baduanjin may be effective exercises to prevent memory decline during aging.

Indexed as

agingBaduanjin exercisehippocampusmedial prefrontal cortexmemory functionTai Chi Chuan exercise

Identifiers

PMID26909038
PMCPMC4754402

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.