ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2016
Postobstructive Pneumonia: An Underdescribed Syndrome.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 40 citations in OpenAlex.
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- Comparison between community-acquired pneumonia and post-obstructive pneumonia associated with endobronchial tumors.BMC pulmonary medicine · 2024Article
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- CT Characteristics and Clinical Findings of Bronchopneumonia Caused by Pepper Aspiration.International journal of general medicine · 2024Article
- Transarterial infusion chemotherapy for advanced esophageal cancer with airway stenosis.Frontiers in oncology · 2023Article
- Early post-discharge mortality in CAP: frequency, risk factors and a prediction tool.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022Observational
- Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancer.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2022Article
- Risk Factors for Infections, Antibiotic Therapy, and Its Impact on Cancer Therapy Outcomes for Patients with Solid Tumors.Life (Basel, Switzerland) · 2021Review
- Infections in Hospitalized Cancer Patients.World journal of oncology · 2021Review
- Is it just a simple pneumonia?Clinical case reports · 2021Article
- Risk factors for post-bronchoscopy pneumonia: a case-control study.Scientific reports · 2020Article
- Etiology of Community-Acquired Pneumonia Requiring Hospital Admission in Adults with and Without Cancers: A Single-Center Retrospective Study in China.Infection and drug resistance · 2020Article
- Postobstructive pneumonia in lung cancer.Annals of translational medicine · 2019Review
- Post-Obstructive Pneumonia in Patients with Cancer: A Review.Infectious diseases and therapy · 2018Review
- Malignant central airway obstruction.Journal of thoracic disease · 2017Review
- Article
- Infections in Cancer Patients with Solid Tumors: A Review.Infectious diseases and therapy · 2017Review
- Diagnosis of lung cancer by flexible fiberoptic bronchoscopy: a descriptive study.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
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8 authors at 5 institutions in 1 country.
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Abstract
backgroundPostobstructive community-acquired pneumonia (PO-CAP) is relatively common in clinical practice. The clinical syndrome is poorly defined, and the role of infection as a cause of the infiltrate is uncertain. We prospectively studied patients with PO-CAP and compared them to a cohort of patients with bacterial community-acquired pneumonia (B-CAP).
methodsWe prospectively studied patients hospitalized for CAP; 5.4% had PO-CAP, defined as a pulmonary infiltrate occurring distal to an obstructed bronchus. Sputum and blood cultures, viral polymerase chain reaction, urinary antigen tests, and serum procalcitonin (PCT) were done in nearly all cases. Clinical and laboratory characteristics of patients with PO-CAP were compared to those of patients with B-CAP.
resultsIn a 2-year period, we identified 30 patients with PO-CAP. Compared to patients with B-CAP, patients with PO-CAP had longer duration of symptoms (median, 14 vs 5 days;P< .001). Weight loss and cavitary lesions were more common (P< .01 for both comparisons) and leukocytosis was less common (P< .01) in patients with PO-CAP. A bacterial pathogen was implicated in only 3 (10%) PO-CAP cases. PCT was <0.25 ng/mL in 19 (63.3%) patients. Although no differences were observed in disease severity or rates of intensive care unit admissions, 30-day mortality was significantly higher in PO-CAP vs B-CAP (40.0% vs 11.7%;P< .01).
conclusionsAlthough there is substantial overlap, PO-CAP is a clinical entity distinct from B-CAP; a bacterial cause was identified in only 10% of patients. Our study has important implications for the clinical recognition of patients with PO-CAP, the role of microorganisms as etiologic agents, and the use of antibiotic therapy.
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