ArticlePediatrics2016
Change in Weight Status and Development of Hypertension.
Article in Pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Prevalence of high blood pressure and hypertension among children and adolescents in Europe: a systematic review and meta-analysis.Archives of disease in childhood · 2026Pooled it
- The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2026Guideline
- Cardiovascular morbidity, diabetes and cancer risk among children and adolescents with severe obesity.Cardiovascular diabetology · 2020Pooled it
- The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019).Hypertension research : official journal of the Japanese Society of Hypertension · 2019Guideline
- Updated Guideline May Improve the Recognition and Diagnosis of Hypertension in Children and Adolescents; Review of the 2017 AAP Blood Pressure Clinical Practice Guideline.Current hypertension reports · 2017Pooled it
- Cardiometabolic outcome of MyBFF@school intervention program among secondary schoolchildren: a cluster randomized controlled trial.BMC public health · 2026Trial
- Physical Activity as a Predictor of Changes in Systolic Blood Pressure for African-American Adolescents Seeking Treatment for Obesity.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2019Trial
- Anti-obesity medications in children and adolescents: blood pressure and chronic kidney disease implications.Pediatric nephrology (Berlin, Germany) · 2026Review
- Obesity and severe obesity prevalence among youth aged 2-17 in Minnesota, 2020-2025.Preventive medicine reports · 2026Article
- Prevalence and predictors of pediatric high blood pressure: an Egyptian school-based survey.BMC public health · 2026Article
- Postweaning diet affects offspring metabolic outcomes more than maternal diet in male and female mice.Physiological reports · 2026Article
- Novel Waist-to-Height Ratio Estimated Fat Mass Pediatric Cut-offs Predict Hypertension Better than Body Mass Index in Multiracial United States Youths and Adults: The National Health and Nutrition Examination Survey 2015-2023 Cycle.The Journal of nutrition · 2026Article
- Childhood Obesity: A Multisystem Challenge Linking Hypertension, NAFLD, and Sleep Apnea.Medical sciences (Basel, Switzerland) · 2026Review
- Evaluation of Carotid Intima-Media Thickness and Other Cardiovascular Risk Factors in Children with Chronic Kidney Disease.Journal of clinical practice and research · 2025Article
- Article
- Association between the depressive symptom trajectories and all-cause mortality in Chinese middle-aged and elderly adults.Scientific reports · 2025Article
- Clinical guidelines for the diagnosis, evaluation, and management of hypertension for Korean children and adolescents: the Korean Working Group of Pediatric Hypertension.Kidney research and clinical practice · 2025Article
- The Study of the Epidemiology of Pediatric Hypertension Registry (SUPERHERO): rationale and methods.American journal of epidemiology · 2024Article
- Article
- The age of the obesity onset is a very important factor for the development of metabolic complications and cardiovascular risk in children and adolescents with severe obesity.European journal of pediatrics · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
objectiveTo examine the association of BMI percentile and change in BMI percentile to change in blood pressure (BP) percentile and development of hypertension (HTN).
methodsThis retrospective cohort included 101 606 subjects age 3 to 17 years from 3 health systems across the United States. Height, weight, and BPs were extracted from electronic health records, and BMI and BP percentiles were computed with the appropriate age, gender, and height charts. Mixed linear regression estimated change in BP percentile, and proportional hazards regression was used to estimate risk of incident HTN associated with BMI percentile and change in BMI percentile.
resultsThe largest increases in BP percentile were observed among children and adolescents who became obese or maintained obesity. Over a median 3.1 years of follow-up, 0.3% of subjects developed HTN. Obese children ages 3 to 11 had twofold increased risk of developing HTN compared with healthy weight children. Obese children and adolescents had a twofold increased risk of developing HTN, and severely obese children had a more than fourfold increased risk. Compared with those who maintained a healthy weight, children and adolescents who became obese or maintained obesity had a more than threefold increased risk of incident HTN.
conclusionsWe observed a strong, statistically significant association between increasing BMI percentile and increases in BP percentile, with risk of incident HTN associated primarily with obesity. The adverse impact of weight gain and obesity in this cohort over a short period underscores the early need for effective strategies for prevention of overweight and obesity.
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