ArticleBMJ open2016
The relationship between red blood cell distribution width and blood pressure abnormal dipping in patients with essential hypertension: a cross-sectional study.
Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Observational
- The biomarkers associated with non-dipper pattern in patients with type 2 diabetes with hypertension.Medicine and pharmacy reports · 2024Article
- Association between red cell distribution width and hypertension: Results from NHANES 1999-2018.PloS one · 2024Article
- The association between red cell distribution width and newly diagnosed hypertension among adults in Northern Sudan: a case-control study.The Libyan journal of medicine · 2023Article
- Review
- Role of sympathetic pathway in light-phase time-restricted feeding-induced blood pressure circadian rhythm alteration.Frontiers in nutrition · 2022Article
- Association between ambulatory blood pressure variability and frailty among older hypertensive patients.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Circadian Blood Pressure Variations Computed From 1.7 Million Measurements in an Acute Hospital Setting.American journal of hypertension · 2019Article
- The role of red blood cell distribution width (RDW) in cardiovascular risk assessment: useful or hype?Annals of translational medicine · 2019Review
- Red cell distribution width associated with adverse cardiovascular outcomes in patients with chronic kidney disease.BMC nephrology · 2017Article
- Clinical and prognostic significance of a reverse dipping pattern on ambulatory monitoring: An updated review.Journal of clinical hypertension (Greenwich, Conn.) · 2017Review
- Red Blood Cell Distribution Width: A Novel Predictive Indicator for Cardiovascular and Cerebrovascular Diseases.Disease markers · 2017Review
- Article
- Aging and Vascular Compliance in Hypertensive Patients Mirrored in Routine Investigations.Current health sciences journalArticle
- Inflammation and Arterial Hypertension-Pathophysiological Links and Clinical Aspects.Current health sciences journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate whether red blood cell distribution width (RDW) is associated with the blood pressure (BP) reverse-dipper pattern in patients with hypertension.
designCross-sectional study.
settingSingle centre.
participantsPatients with essential hypertension were included in our study (n=708). The exclusion criteria included age <18 or >90 years, incomplete clinical data, night workers, diagnosis of secondary hypertension, under antihypertensive treatment, intolerance for the 24 h ambulatory BP monitoring (ABPM) and BP reading success rate <70%. MEASUREMENT: Physical examination and ABPM were performed for all patients in our study. The value of RDW was measured using an automated haematology analyser. STATISTICAL
methodsThe distribution of RDW in patients with hypertension among different circadian BP pattern groups was analyzed using analysis of variance (ANOVA). Multinomial logistic regression was applied to explore the associations of RDW and other relevant variables with ABPM results.
resultsThere was significantly increased RDW in reverse dippers (13.52 ± 1.05) than dippers (13.25 ± 0.85) of hypertension (p=0.012). Moreover, multinomial logistic regression analysis showed that RDW (OR 1.325, 95% CI 1.037 to 1.692, p=0.024) and diabetes mellitus (OR 2.286, 95% CI 1.380 to 3.788, p=0.001) were significantly different when comparing the reverse-dipper BP pattern with the dipper pattern. However, there was no difference of RDW between the non-dipper pattern and the reverse-dipper pattern (OR 1.036, 95% CI 0.867 to 1.238, p=0.693). In addition to this, RDW was negatively correlated with the decline rate of nocturnal systolic BP (r=-0.113; p=0.003) and diastolic BP (r=-0.101; p=0.007).
conclusionsOur results suggested that RDW might associate with the abnormal dipper BP patterns of either reverse dipping or non-dipping homogeneously examined with 24 h ABPM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.