Evidence map›Paper›PMID 26908527›Full record

ArticleBMJ open2016

Use of cannabis during pregnancy and birth outcomes in an Aboriginal birth cohort: a cross-sectional, population-based study.

Stephanie J Brown, Fiona K Mensah, Jackie Ah Kit, Deanna Stuart-Butler, Karen Glover, Cathy Leane, Donna Weetra, Deirdre Gartland, Jonathan Newbury, Jane Yelland

Abstract read
In one paragraph

Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Stephanie J BrownHealthy Mothers Healthy Families Research Group, Murdoch Childrens Research Institute, Parkville, Victoria, Australia General Practice and Primary Health Care Academic Centre, The University of Melbourne, Parkville, Victoria, Australia South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Fiona K MensahClinical Epidemiology and Biostatistics Unit, Department of Pediatrics, Murdoch Childrens Research Institute, Royal Children's Hospital, The University of Melbourne, Parkville, Victoria, Australia.
Jackie Ah KitWomen's and Children's Health Network, SA Health, Adelaide, South Australia, Australia.
Deanna Stuart-ButlerWomen's and Children's Health Network, SA Health, Adelaide, South Australia, Australia.
Karen GloverSouth Australian Health and Medical Research Institute, Adelaide, South Australia, Australia Pangula Mannamurna Inc, Mt Gambier, South Australia, Australia.
Cathy LeaneWomen's and Children's Health Network, SA Health, Adelaide, South Australia, Australia.
Donna WeetraHealthy Mothers Healthy Families Research Group, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.
Deirdre GartlandHealthy Mothers Healthy Families Research Group, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.
Jonathan NewburyDepartment of Rural Health, The University of Adelaide, Adelaide, South Australia, Australia.
Jane YellandHealthy Mothers Healthy Families Research Group, Murdoch Childrens Research Institute, Parkville, Victoria, Australia General Practice and Primary Health Care Academic Centre, The University of Melbourne, Parkville, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIndigenous women continue to experience rates of stillbirth, preterm birth and low birth weight, two to three times higher than other women in high-income countries. The reasons for disparities are complex and multifactorial. We aimed to assess the extent to which adverse birth outcomes are associated with maternal cannabis use and exposure to stressful events and social health issues during pregnancy. DESIGN/

settingCross-sectional, population-based survey of women giving birth to Aboriginal babies in South Australia, July 2011-June 2013. Data include: maternal cannabis use, exposure to stressful events/social health issues, infant birth weight and gestation.

participants344 eligible women with a mean age of 25 years (range 15-43 years), enrolled in the study. Participants were representative in relation to maternal age, infant birth weight and gestation.

results1 in 5 women (20.5%) used cannabis during pregnancy, and 52% smoked cigarettes. Compared with mothers not using cannabis or cigarettes, mothers using cannabis had babies on average 565 g lighter (95% CI -762 to -367), and were more likely to have infants with a low birth weight (OR=6.5, 95% CI 3.0 to 14.3), and small for gestational age (OR=3.8, 95% CI 1.9 to 7.6). Controlling for education and other social characteristics, including stressful events/social health issues did not alter the conclusion that mothers using cannabis experience a higher risk of negative birth outcomes (adjusted OR for odds of low birth weight 3.9, 95% CI 1.4 to 11.2).

conclusionsThe findings provide a compelling case for stronger efforts to address the clustering of risk for adverse outcomes in Aboriginal and Torres Strait Islander communities, and point to the need for antenatal care to address broader social determinants of adverse perinatal outcomes. Integrated responses--collaboratively developed with Aboriginal communities and organisations--that focus on constellations of risk factors, and a holistic approach to addressing social determinants of adverse birth outcomes, are required.

Indexed as

Infant, Low Birth WeightAdolescentAdultAustralian Aboriginal and Torres Strait Islander PeoplesCannabisCross-Sectional StudiesFemaleHumansInfant, NewbornMarijuana SmokingPregnancyPregnancy OutcomePremature BirthPrenatal Exposure Delayed EffectsRisk FactorsSmokingEPIDEMIOLOGYMENTAL HEALTHOBSTETRICSPRIMARY CARE

Identifiers

PMID26908527
PMCPMC4769386

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.