Evidence map›Paper›PMID 26908490›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2016

Factors Associated With Retention Among Non-Perinatally HIV-Infected Youth in the HIV Research Network.

Charles Farmer, Baligh R Yehia, John A Fleishman, Richard Rutstein, W Christopher Mathews, Ank Nijhawan, Richard D Moore, Kelly A Gebo, Allison L Agwu, HIV Research Network

Abstract read
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Time to Engage Young People in HIV Cure Research.AIDS research and human retroviruses · 2022
    Article
  4. Article
  5. Article
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  13. Review
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  15. Article
  16. Article
  17. Article
  18. Aging and loss to follow-up among youth living with human immunodeficiency virus in the HIV Research Network.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Charles FarmerJohns Hopkins School of Medicine, Baltimore, Maryland.
Baligh R YehiaDivision of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia.
John A FleishmanCenter for Financing, Access, and Cost Trends, Agency for Healthcare Research and Quality, Rockville, Maryland.
Richard RutsteinDivision of General Pediatrics, Children's Hospital of Philadelphia, Pennsylvania.
W Christopher MathewsDepartment of Clinical Medicine, University of California San Diego Medical Center.
Ank NijhawanDepartment of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.
Richard D MooreDivision of General Internal Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Kelly A GeboDivision of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Allison L AgwuDivision of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland.
HIV Research Network

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Reducing Readmissions and Improving Outcomes in HIV-Infected PatientsK23AI112477 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI NIJHAWAN, ANK ELISABETH · 2015 to 2018
$703k
HAART Initiation in Behaviorally HIV-Infected YouthK23AI084549 · NIAID · JOHNS HOPKINS UNIVERSITY · PI AGWU, ALLISON L · 2010 to 2013
$537k
Evaluating Patient Retention in HIV CareK23MH097647 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI YEHIA, BALIGH RAMZI · 2012 to 2013
$361k
NIAID NIH HHS 1K23AI084549-01A1NIAID NIH HHS K23 AI084549NIAID NIH HHS K23 AI112477NIAID NIH HHS P30 AI045008NIAID NIH HHS P30 AI094189NIMH NIH HHS K23 MH097647NIMH NIH HHS K23-MH097647PHS HHS 290-11-00007CPHS HHS 90051652
6 · The paper itself

Abstract

backgroundThe transmission of human immunodeficiency virus (HIV) among youth through high-risk behaviors continues to increase. Retention in Care is associated with positive clinical outcomes and a decrease in HIV transmission risk behaviors. We evaluated the clinical and demographic characteristics of non-perinatally HIV (nPHIV)-infected youth associated with retention 1 year after initiating care and in the 2 years thereafter. We also assessed the impact retention in year 1 had on retention in years 2 and 3.

methodsThis was a retrospective analysis of treatment-naive nPHIV-infected 12- to 24-year-old youth presenting for care in 16 US HIV clinical sites within the HIV Research Network between 2002 and 2008. Multivariate logistic regression identified factors associated with retention.

resultsOf 1160 nPHIV-infected youth, 44.6% were retained in care during the first year, and 22.4% were retained in all 3 years. Retention in the first year was associated with starting antiretroviral therapy in the first year (adjusted odds ratio [AOR], 3.47 [95% confidence interval (CI), 2.57-4.67]), Hispanic ethnicity (AOR, 1.66 [95% CI, 1.08-2.56]), men who have sex with men (AOR, 1.59 [95% CI, 1.07-2.36]), and receiving care at a pediatric site (AOR, 5.37 [95% CI, 3.20-9.01]). Retention in years 2 and 3 was associated with being retained 1 year after initiating care (AOR, 7.44 [95% CI, 5.11-10.83]).

conclusionA high proportion of newly enrolled nPHIV-infected youth were not retained for 1 year, and only 1 in 4 were retained for 3 years. Patients who were Hispanic, were men who have sex with men, or were seen at pediatric clinics were more likely to be retained in care. Interventions that target those at risk of being lost to follow up are essential for this high-risk population.

Indexed as

Delivery of Health CareAdolescentChildEthnicityFemaleHIV InfectionsHomosexuality, MaleHospitals, PediatricHumansInsurance CoverageMaleRetrospective StudiesRisk FactorsUnited StatesYoung AdultadolescentsHIV Research Networkretentionyouth

Identifiers

PMID26908490
PMCPMC4765490

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.