ArticleJournal of neurogastroenterology and motility2016
Long-term Clinical Course of Post-infectious Irritable Bowel Syndrome After Shigellosis: A 10-year Follow-up Study.
Article in Journal of neurogastroenterology and motility, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Prevalence, Risk Factors, and Outcomes of Irritable Bowel Syndrome After Infectious Enteritis: A Systematic Review and Meta-analysis.Gastroenterology · 2017Pooled it
- Gut microbiome dynamics in acute infectious diarrhea: A conceptual framework from acute dysbiosis toward precision restoration (Review).Experimental and therapeutic medicine · 2026Review
- Risk Factors of Developing Postinfectious Irritable Bowel Syndrome in Shigellosis Patients, 5 Years After Hospitalization During the Outbreak.Open forum infectious diseases · 2024Article
- Effects of Unconventional Work and Shift Work on the Human Gut Microbiota and the Potential of Probiotics to Restore Dysbiosis.Nutrients · 2023Review
- Laparoscopic Heller-Dor is an effective long-term treatment for end-stage achalasia.Surgical endoscopy · 2023Article
- Health care utilizations and costs of Campylobacter enteritis in Germany: A claims data analysis.PloS one · 2023Article
- Development of functional gastrointestinal disorder symptoms following laparoscopic cholecystectomy: a prospective cohort study.Frontiers in medicine · 2023Article
- Association between infections and functional somatic disorders: a cross-sectional population-based cohort study.BMJ open · 2022Article
- Article
- Global burden of irritable bowel syndrome: trends, predictions and risk factors.Nature reviews. Gastroenterology & hepatology · 2020Review
- Microbiota: a novel regulator of pain.Journal of neural transmission (Vienna, Austria : 1996) · 2020Review
- Chronic Gastrointestinal and Joint-Related Sequelae Associated with Common Foodborne Illnesses: A Scoping Review.Foodborne pathogens and disease · 2020Article
- Fluoxetine ameliorates dysbiosis in a depression model induced by chronic unpredicted mild stress in mice.International journal of medical sciences · 2019Article
- Post-infectious IBS, tropical sprue and small intestinal bacterial overgrowth: the missing link.Nature reviews. Gastroenterology & hepatology · 2017Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsA limited number of studies are available regarding the long-term natural history of post-infectious irritable bowel syndrome (PI-IBS). We aimed to investigate the long-term clinical course of PI-IBS.
methodsA prospective cohort study was conducted from a 2001 shigellosis outbreak in a Korean hospital with about 2000 employees. A cohort of 124 hospital employees who were infected by Shigella sonnei due to contaminated food in the cafeteria, and 105 sex- and age-matched, non-infected, controls were serially followed for their bowel symptoms by questionnaire surveys for 10 years.
resultsThe Shigella -infected cohort showed significantly higher odds ratio for irritable bowel syndrome (IBS) at 1-year (11.90; 95% CI, 1.49-95.58) and 3-year (3.93; 95% CI, 1.20-12.86) follow-up, compared to their controls. However, corresponding odds ratio for PI-IBS was not significantly increased at 5-year (1.88; 95% CI, 0.64-5.54) and 8-year (1.87; 95% CI, 0.62-5.19) follow-up. At 10-year follow-up survey, the prevalence of IBS was similar for the Shigella -infected cohort and their controls (23.3% versus 19.7%, P = 0.703). Risk factors which were independently associated with PI-IBS among the Shigella -infected cohort included younger age, previous history of functional bowel disorder, and longer duration of diarrhea at baseline.
conclusionsPatients who were infected by Shigella sonnei experienced significantly increased risk of IBS until 3 years after shigellosis, and modestly increased risk until 8 years, but showed similar risk of IBS with uninfected controls at 10 years post-infection. PI-IBS is quite a chronic disorder, and follows a long-term natural course.
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Registered trials
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