ArticleBrain structure & function2017
Connectivity between the central nucleus of the amygdala and the bed nucleus of the stria terminalis in the non-human primate: neuronal tract tracing and developmental neuroimaging studies.
Article in Brain structure & function, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
56 citing papers in PubMed, 83 citations in OpenAlex.
- Intricate mesoscale organization of the anterior commissure in the rhesus monkey, with implications for neuroimaging.Brain structure & function · 2026Article
- Comparing the Limbic-Frontal Connectome across the Primate Order: Conservation of Connections and Implications for Translational Neuroscience.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Article
- Acute and chronic alcohol modulation of extended amygdala calcium dynamics.Alcohol (Fayetteville, N.Y.) · 2024Article
- Early life adversity in primates: Behavioral, endocrine, and neural effects.Psychoneuroendocrinology · 2024Article
- Understanding the heterogeneity of anxiety using a translational neuroscience approach.Cognitive, affective & behavioral neuroscience · 2024Review
- A novel subdivision of the bed nucleus of stria terminalis in monkey, rat, and mouse brains.The Journal of comparative neurology · 2023Article
- Acute and chronic alcohol modulation of extended amygdala calcium dynamics.bioRxiv : the preprint server for biology · 2023Article
- Somatostatin neurons in the central amygdala mediate anxiety by disinhibition of the central sublenticular extended amygdala.Molecular psychiatry · 2023Article
- Pharmacological Inactivation of the Bed Nucleus of the Stria Terminalis Increases Affiliative Social Behavior in Rhesus Macaques.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Editorial: Current advances in multimodal human brain imaging and analysis across the lifespan: From mapping to state prediction.Frontiers in neuroscience · 2023Article
- The neurophysiological basis of stress and anxiety - comparing neuronal diversity in the bed nucleus of the stria terminalis (BNST) across species.Frontiers in cellular neuroscience · 2023Review
- Corticotropin Releasing Factor (CRF) Coexpression in GABAergic, Glutamatergic, and GABA/Glutamatergic Subpopulations in the Central Extended Amygdala and Ventral Pallidum of Young Male Primates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- The central extended amygdala guides survival-relevant tradeoffs: Implications for understanding common psychiatric disorders.Neuroscience and biobehavioral reviews · 2022Article
- Effects of Anesthesia on Cerebral Blood Flow and Functional Connectivity of Nonhuman Primates.Veterinary sciences · 2022Review
- Regulation of alcohol drinking by ventral striatum and extended amygdala circuitry.Neuropharmacology · 2022Review
- Subiculum-BNST structural connectivity in humans and macaques.NeuroImage · 2022Article
- Altered hippocampus and amygdala subregion connectome hierarchy in major depressive disorder.Translational psychiatry · 2022Article
- Perturbation of amygdala/somatostatin-nucleus of the solitary tract projections reduces sensitivity to quinine in a brief-access test.Brain research · 2022Article
- Prefrontal connectomics: from anatomy to human imaging.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
The lateral division of the bed nucleus of the stria terminalis (BSTL) and central nucleus of the amygdala (Ce) form the two poles of the 'central extended amygdala', a theorized subcortical macrostructure important in threat-related processing. Our previous work in nonhuman primates, and humans, demonstrating strong resting fMRI connectivity between the Ce and BSTL regions, provides evidence for the integrated activity of these structures. To further understand the anatomical substrates that underlie this coordinated function, and to investigate the integrity of the central extended amygdala early in life, we examined the intrinsic connectivity between the Ce and BSTL in non-human primates using ex vivo neuronal tract tracing, and in vivo diffusion-weighted imaging and resting fMRI techniques. The tracing studies revealed that BSTL receives strong input from Ce; however, the reciprocal pathway is less robust, implying that the primate Ce is a major modulator of BSTL function. The sublenticular extended amygdala (SLEAc) is strongly and reciprocally connected to both Ce and BSTL, potentially allowing the SLEAc to modulate information flow between the two structures. Longitudinal early-life structural imaging in a separate cohort of monkeys revealed that extended amygdala white matter pathways are in place as early as 3 weeks of age. Interestingly, resting functional connectivity between Ce and BSTL regions increases in coherence from 3 to 7 weeks of age. Taken together, these findings demonstrate a time period during which information flow between Ce and BSTL undergoes postnatal developmental changes likely via direct Ce → BSTL and/or Ce ↔ SLEAc ↔ BSTL projections.
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