Evidence map›Paper›PMID 26908165›Full record

ArticleEnvironment international2016

Neighborhood deprivation, race/ethnicity, and urinary metal concentrations among young girls in California.

Felisa A Gonzales, Rena R Jones, Julianna Deardorff, Gayle C Windham, Robert A Hiatt, Lawrence H Kushi

Open access · greenAbstract read
In one paragraph

Article in Environment international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Testing the Multiple Disadvantage Model of Health with Ethnic Asian Children: A Secondary Data Analysis.International journal of environmental research and public health · 2022
    Article
  3. Article
  4. Review
  5. Inaction on Lead Despite the Relevant Knowledge: Predictors, Covariates, and Outreach Implications.International journal of environmental research and public health · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Felisa A GonzalesNational Cancer Institute, Health Systems and Interventions Research Branch, Healthcare Delivery Research Program, Division of Cancer Control and Population Sciences, BG 9609 RM 3E502 MSC 9712, 9609 Medical Center Drive, Rockville, MD 20850-9712, United States. Electronic address: felisa.gonzales@nih.gov.
Rena R JonesNational Cancer Institute, Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, BG 9609 RM 6E124 MSC 9771, 9609 Medical Center Drive, Rockville, MD 20850-9771, United States. Electronic address: rena.jones@nih.gov.
Julianna DeardorffUniversity of California at Berkeley, School of Public Health, Department of Community Health and Human Development, 50 University Hall #7360, Berkeley, CA 94720-7360, United States. Electronic address: jdeardorff@berkeley.edu.
Gayle C WindhamCalifornia Department of Public Health, Environmental Health Investigations Branch, 850 Marina Bay Parkway, Building P, 3rd Floor, Richmond, CA 94804, United States. Electronic address: Gayle.Windham@cdph.ca.gov.
Robert A HiattUniversity of California at San Francisco, Department of Epidemiology and Biostatistics, Helen Diller Family Comprehensive Cancer Center, Box 0560, San Francisco, CA 94143-0560, United States. Electronic address: robert.hiatt@ucsf.edu.
Lawrence H KushiKaiser Permanente, Division of Research, 2000 Broadway, Oakland, CA 94612, United States. Electronic address: larry.kushi@kp.org.
California Department of Public Health · USDivision of Cancer Epidemiology and GeneticsKaiser Permanente · USNational Cancer Institute · USUCSF Helen Diller Family Comprehensive Cancer Center · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Bay Area Breast Cancer &the Environment Research CenterU01ES012801 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HIATT, ROBERT A · 2003 to 2010
$12.4M
The CYGNET Study: Enviromental and Genetic Determinants of Maturation of GirlsU01ES019435 · NIEHS · KAISER FOUNDATION RESEARCH INSTITUTE · PI KUSHI, LAWRENCE H · 2010 to 2015
$4.9M
Meeting AccountU01ES019457 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HIATT, ROBERT A · 2010 to 2014
$3.2M
Intramural NIH HHS Z99 CA999999NCRR NIH HHS UL1 RR024131NCRR NIH HHS UL1RR024131NIEHS NIH HHS U01 ES012801NIEHS NIH HHS U01ES012801NIEHS NIH HHS U01 ES019435NIEHS NIH HHS U01ES019435 ANDNIEHS NIH HHS U01 ES019457NIEHS NIH HHS U01ES019457
6 · The paper itself

Abstract

backgroundAlthough metals can adversely impact children's health, the distribution of exposures to many metals, particularly among vulnerable subpopulations, is not well characterized.

objectivesWe sought to determine whether neighborhood deprivation was associated with urinary concentrations of thirteen metals and whether observed relationships varied by race/ethnicity.

methodsWe obtained neighborhood characteristics from the 2005-2009 American Community Survey. Demographic information and urine samples from 400 healthy young girls in Northern California were obtained during a clinical visit. Urine samples were analyzed for metals using inductively-coupled plasma-mass spectrometry and levels were corrected for creatinine. We ran analysis of variance and generalized linear regression models to estimate associations of urinary metal concentrations with neighborhood deprivation and race/ethnicity and stratified multivariable models to evaluate possible interactions among predictors on metals concentrations.

resultsUrinary concentrations of three metals (barium, lead, antimony) varied significantly across neighborhood deprivation quartiles, and four (barium, lead, antimony, tin) varied across race/ethnicity groups. In models adjusted for family income and cotinine, both race/ethnicity (F3,224=4.34, p=0.01) and neighborhood deprivation (F3,224=4.32, p=0.01) were associated with antimony concentrations, but neither were associated with lead, barium, or tin, concentrations. Examining neighborhood deprivation within race/ethnicity groups, barium levels (pinteraction<0.01) decreased with neighborhood deprivation among Hispanic girls (ptrend<0.001) and lead levels (pinteraction=0.06) increased with neighborhood deprivation among Asian girls (ptrend=0.04).

conclusionsOur results indicate that children's vulnerability to some metals varies by neighborhood deprivation quartile and race/ethnicity. These differential distributions of exposures may contribute to environmental health disparities later in life.

Indexed as

CaliforniaChildEnvironmental MonitoringEnvironmental PollutantsEthnicityFemaleHumansIncomeMetalsRacial GroupsResidence CharacteristicsEnvironmental PollutantsMetalsChildrenEnvironmental health disparitiesLeadMetalsVulnerability

Identifiers

PMID26908165
PMCPMC6360017
OpenAlexW2280547483

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.