ArticlePloS one2016
The Prevalence of Peyronie's Disease in the United States: A Population-Based Study.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 4 syntheses or guidelines pooled it, 135 citations in OpenAlex.
- A Systematic Review on Administration of Botulinum Toxin in the Management of Male Sexual Dysfunctions.Andrology · 2026Pooled it
- Updated recommendations on the therapeutic role of extracorporeal shock wave therapy for peyronie's disease: systematic review and meta-analysis.BMC urology · 2023Pooled it
- The Immunological Microenvironment and the Emerging Role of Stem Cells Therapy in Peyronie's Disease: A Systematic Narrative Review.International journal of molecular sciences · 2023Pooled it
- Peyronie's disease and testosterone deficiency: Is there a link?World journal of urology · 2019Pooled it
- Patient perspectives on Peyronie's disease: results of poststudy interviews from a phase 2 trial of collagenase clostridium histolyticum.International journal of impotence research · 2019Trial
- Perception and Reality of Postoperative Penile Length in Men Undergoing Plaque Excision and Grafting for Peyronie's Disease.International journal of impotence research · 2026Article
- Peyronie's disease in Spain: a prospective study.Sexual medicine · 2026Article
- Use of Himplant® for correction of residual deformity following prior treatment of peyronie's disease: a case series.International journal of impotence research · 2026Review
- Cost Consideration for the Treatment of Peyronie's Disease: A Narrative Review.Current urology reports · 2025Review
- MRI of the Scrotum and Penis: Current Applications and Clinical Relevance.Diagnostics (Basel, Switzerland) · 2025Review
- Comparative outcomes of intralesional collagenase injection for Peyronie's disease: acute vs. stable phase treatment.International journal of impotence research · 2025Article
- Epigenetic differences in non-plaque tissues of men with Peyronie's disease.The journal of sexual medicine · 2025Article
- Article
- Benchmarking bias in embeddings of healthcare AI models: using SD-WEAT for detection and measurement across sensitive populations.BMC medical informatics and decision making · 2025Article
- Platelet-rich plasma intra-plaque injections rapidly reduce penile curvature and improve sexual function in Peyronie's disease patients: results from a prospective large-cohort study.World journal of urology · 2025Article
- Oxidative Mechanism of Peyronie's Disease and Effectiveness of Pentoxifylline in the Therapeutic Management: A Narrative Review.Antioxidants (Basel, Switzerland) · 2025Review
- Late-Onset Penile Fracture After CollagenaseCase reports in urology · 2025Article
- An overview of the Canadian landscape on the use of restorative therapies for erectile dysfunction and Peyronie's disease.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024Article
- Plication surgery does not produce additional loss of length in Peyronie's disease patients.International journal of impotence research · 2024Article
- Development of a new Peyronie's disease self-assessment screening app.Translational andrology and urology · 2024Review
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Peyronie's disease (PD) is a connective tissue disorder which can result in penile deformity. The prevalence of diagnosed PD in the United States (US) has been estimated to be 0.5% in adult males, but there is limited additional information comparing definitive and probable PD cases. We conducted a population-based survey to assess PD prevalence using a convenience-sample of adult men participating in the ResearchNow general population panel. Respondents were categorized according to PD status (definitive, probable, no PD) and segmented by US geographic region, education, and income levels. Of the 7,711 respondents, 57 (0.7%) had definitive PD while 850 (11.0%) had probable PD. Using univariate logistic regression modeling, older age (18-24 vs 24+) (OR = 0.721; 95% CI = 0.570,0.913), Midwest/Northeast/West geographic region (South vs Midwest/Northeast/West) (OR = 0.747; 95% CI = 0.646,0.864), and higher income level (<25K vs 25K+) (OR = 0.820; 95% CI = 0.673,0.997) were each significantly associated with reduced odds of having a definitive/probable PD diagnosis compared with no PD diagnosis. When all three variables were entered in a stepwise multivariable logistic regression, only age (OR = 0.642; 95% CI = 0.497, 0.828) and region (OR = 0.752; 95% CI = 0.647, 0.872) remained significant. This study is the first to report PD prevalence by geographic region and income, and it advocates that the prevalence of PD in the US may be higher than previously cited. Further, given the large discrepancy between definitive PD cases diagnosed by a physician and probable cases not diagnosed by a physician, much more needs to be done to raise awareness of this disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.