ReviewToxins2016
Venoms of Heteropteran Insects: A Treasure Trove of Diverse Pharmacological Toolkits.
Review in Toxins, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 92 citations in OpenAlex.
- Multifunctional lysozymes from the assassin bug Sycanus bifidus: Insecticidal proteins with anticoagulant and melanization inhibition properties.Pest management science · 2026Article
- The venom-specific toxicity profiles of the mirid bug Tytthus chinensis to its prey insect Nilaparvata lugens.Pest management science · 2026Article
- Morphological and Ultrastructural Characterization of the Venom Apparatus of the Predatory Stink Bug,Insects · 2026Article
- Insights into platypus crural gland transcriptomics - venom and beyond.BMC genomics · 2025Article
- Comprehensive Analysis of Cathepsin Genes in Hemiptera: Functional Characterization of the Venomous Cathepsin B fromInsects · 2025Article
- Hemipteran insects experience recurrent and synergistic molecular evolution adapting to diet shift.BMC biology · 2025Article
- Antischistosomal Potential of Animal-Derived Natural Products and Compounds.Microorganisms · 2025Review
- Article
- Microbial Community Structure and Metabolic Function in the Venom Glands of the Predatory Stink Bug,Insects · 2024Article
- Venom exaptation and adaptation during the trophic switch to blood-feeding by kissing bugs.iScience · 2024Article
- The venom and telopodal defence systems of the centipede Lithobius forficatus are functionally convergent serial homologues.BMC biology · 2024Article
- CGRP Antagonism and Ketogenic Diet in the Treatment of Migraine.Medicina (Kaunas, Lithuania) · 2024Review
- Consumptive and Non-Consumptive Uses of Water Beetles (Insects · 2023Article
- A Designed Analog of an Antimicrobial Peptide, Crabrolin, Exhibits Enhanced Anti-Proliferative and In Vivo Antimicrobial Activity.International journal of molecular sciences · 2023Article
- The Predatory Stink BugBiology · 2023Article
- An Assassin's Secret: Multifunctional Cytotoxic Compounds in the Predation Venom of the Assassin BugToxins · 2023Article
- Identification and functional analysis of serine protease inhibitor gene family ofFrontiers in physiology · 2023Article
- Transcriptome analysis reveals salivary gland-specific neuropeptide signaling genes in the predatory stink bug,Frontiers in physiology · 2023Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The piercing-sucking mouthparts of the true bugs (Insecta: Hemiptera: Heteroptera) have allowed diversification from a plant-feeding ancestor into a wide range of trophic strategies that include predation and blood-feeding. Crucial to the success of each of these strategies is the injection of venom. Here we review the current state of knowledge with regard to heteropteran venoms. Predaceous species produce venoms that induce rapid paralysis and liquefaction. These venoms are powerfully insecticidal, and may cause paralysis or death when injected into vertebrates. Disulfide-rich peptides, bioactive phospholipids, small molecules such as N,N-dimethylaniline and 1,2,5-trithiepane, and toxic enzymes such as phospholipase A2, have been reported in predatory venoms. However, the detailed composition and molecular targets of predatory venoms are largely unknown. In contrast, recent research into blood-feeding heteropterans has revealed the structure and function of many protein and non-protein components that facilitate acquisition of blood meals. Blood-feeding venoms lack paralytic or liquefying activity but instead are cocktails of pharmacological modulators that disable the host haemostatic systems simultaneously at multiple points. The multiple ways venom is used by heteropterans suggests that further study will reveal heteropteran venom components with a wide range of bioactivities that may be recruited for use as bioinsecticides, human therapeutics, and pharmacological tools.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.